Xanthine oxidase inhibitory activity of nicotino/isonicotinohydrazides: A systematic approach from in vitro, in silico to in vivo studies

[Display omitted] Change in life style and eating habits has led to an increased prevalence of hyperuricemia worldwide. The role of hyperuricemia is no more restricted to gout, but it has a central role in progression of CVD, hypertension, metabolic syndrome, and arthritis. Among the different facto...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2017-04, Vol.25 (8), p.2351-2371
Hauptverfasser: Zafar, Humaira, Hayat, Muhammad, Saied, Sumayya, Khan, Momin, Salar, Uzma, Malik, Rizwana, Choudhary, M. Iqbal, Khan, Khalid Mohammed
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Sprache:eng
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