Treatment of Hematological Malignancies with Glycyrrhizic Acid

The current study examined the effectiveness of glycyrrhizic acid (GA) in reducing cell viability and inducing apoptosis in human chronic myeloid leukemia (CML) in vitro and a mouse lymphoma in vivo. Additionally, we assessed GA as a candidate for combinational therapy in CML along with the current...

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Veröffentlicht in:	Anticancer research 2017-03, Vol.37 (3), p.997-1004
Hauptverfasser:	Hostetler, Bryan J, Uchakina, Olga N, Ban, Hao, McKallip, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - therapeutic use Apoptosis Cell Line, Tumor Cell Survival Glycyrrhizic Acid - therapeutic use Hematologic Neoplasms - drug therapy Humans Imatinib Mesylate - therapeutic use K562 Cells Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Leukocytes, Mononuclear - cytology Lymphoma - drug therapy Mice Neoplasm Transplantation Reactive Oxygen Species - metabolism
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