Elevated Preoperative Serum CEA Level Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma Through the Epithelial-Mesenchymal Transition

Serum carcinoembryonic antigen (CEA) is used as an indicator of tumor progression in a variety of carcinomas. A subset of patients with hepatocellular carcinoma (HCC) exhibit increased serum CEA level, but the significance of this is unclear. In this study, we investigated the prognosis of patients...

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Veröffentlicht in:	Anticancer research 2017-03, Vol.37 (3), p.1169-1176
Hauptverfasser:	Yoshikawa, Masato, Morine, Yuji, Ikemoto, Tetsuya, Imura, Satoru, Higashijima, Jun, Iwahashi, Shuichi, Saito, Y U, Takasu, Chie, Yamada, Shinichiro, Ishikawa, Daichi, Teraoku, Hiroki, Takata, Atsushi, Yoshimoto, Toshiaki, Shimada, Mitsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens, CD - metabolism Antigens, CD34 - metabolism Cadherins - metabolism Carcinoembryonic Antigen - blood Carcinoma, Hepatocellular - blood Carcinoma, Hepatocellular - surgery Cell Adhesion Molecules - metabolism Disease-Free Survival Epithelial-Mesenchymal Transition Female Follow-Up Studies Humans Immunohistochemistry Liver Neoplasms - blood Liver Neoplasms - surgery Male Microcirculation Middle Aged Neovascularization, Pathologic Predictive Value of Tests Preoperative Period Prognosis Recurrence Vimentin - metabolism
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