Age-related changes in mature CD4 super(+) T cells: cell cycle analysis

T cell proliferative responses decrease with age, but the mechanisms responsible are unknown. We examined the impact of age on memory and naive CD4 super(+) T cell entry and progression through the cell cycle using acridine orange to identify cell cycle stage. For both subsets, fewer stimulated cell...

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Veröffentlicht in:Cellular immunology 2002-11, Vol.220 (1), p.51-62
Hauptverfasser: Hale, T J, Richardson, B C, Sweet, LI, McElligott, D L, Riggs, JE, Chu, E B, Glynn, J M, LaFrenz, D, Ernst, D N, Rochford, R, Hobbs, M V
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Sprache:eng
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