Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass

Impaired β-cell function and insufficient β-cell mass compensation are twin pathogenic features that underlie type 2 diabetes (T2D). Current therapeutic strategies continue to evolve to improve treatment outcomes in different ethnic populations and include approaches to counter insulin resistance an...

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Veröffentlicht in:	European journal of clinical nutrition 2017-07, Vol.71 (7), p.896-903
Hauptverfasser:	Shirakawa, J, De Jesus, D F, Kulkarni, R N
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443/319 631/80/83 64/60 692/163/2743/137/773 82/51 96/95 Adiposity Animals Antidiabetics Beta cells Biology Blood Glucose - physiology Clinical Nutrition Crosstalk Databases, Factual Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - drug therapy Disease Models, Animal Endothelial cells Endothelial Cells - physiology Epidemiology Gastrointestinal Microbiome Gastrointestinal system Gastrointestinal Tract - microbiology Gastrointestinal Tract - physiology Homeostasis Humans Hyperglycemia Hyperglycemia - drug therapy Hypoglycemic Agents - pharmacology Immune system Innervation Insulin Insulin - metabolism Insulin resistance Insulin Secretion Insulin-Secreting Cells - physiology Internal Medicine Islet cells Liver - physiology Medicine Medicine & Public Health Metabolic Diseases Metabolism Microbiomes Minority & ethnic groups Muscle, Skeletal - physiology Muscles Nervous system Neurons - physiology Organs Patients Pituitary Populations Public Health Reproductive organs review Skeletal muscle Thyroid
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