Similarities and differences between coronary heart disease and stroke in the associations with cardiovascular risk factors: The Japan collaborative cohort study
Abstract Background and aims Coronary heart disease (CHD) and stroke have common risk factors, but some of these differ in the magnitude or direction of associations between CHD and stroke. We assessed whether the impact of each risk factor differed between CHD and stroke mortality in Asians. Method...
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| Veröffentlicht in: | Atherosclerosis 2017-06, Vol.261, p.124-130 |
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| creator | Matsunaga, Masaaki Yatsuya, Hiroshi Iso, Hiroyasu Yamashita, Kentaro Li, Yuanying Yamagishi, Kazumasa Tanabe, Naohito Wada, Yasuhiko Wang, Chaochen Ota, Atsuhiko Tamakoshi, Koji Tamakoshi, Akiko |
| description | Abstract Background and aims Coronary heart disease (CHD) and stroke have common risk factors, but some of these differ in the magnitude or direction of associations between CHD and stroke. We assessed whether the impact of each risk factor differed between CHD and stroke mortality in Asians. Methods In total, 104 910 subjects aged 40–79 years without histories of cancer, CHD and stroke at baseline were followed between 1988 and 2009. Competing-risks analysis was used to test for differences in the associations of each risk factor with two endpoints (CHD and stroke). Population attributable fractions (PAFs) were also calculated for these endpoints to estimate the population impact of each risk factor. Results During a median 19.1-year follow-up, 1554 died from CHD and 3163 from stroke. The association of hypertension with CHD was similar to that with stroke in terms of the magnitude and direction (multivariable-adjusted hazard ratio for CHD: 1.63 vs. stroke: 1.73 in men and 1.70 vs. 1.66 in women). Conversely, the magnitude of these associations differed for smoking (CHD: 1.95 vs. stroke: 1.23 in men and 2.45 vs. 1.35 in women) and diabetes (1.49 vs. 1.09 in men and 2.08 vs. 1.39 in women). The highest PAF for CHD was caused by smoking in men and by hypertension in women; that for stroke was caused by hypertension in both sexes. Conclusions Hypertension associations and PAFs were consistent between CHD and stroke, but not for other risk factors. These findings may be useful to optimize public health intervention strategies. |
| doi_str_mv | 10.1016/j.atherosclerosis.2017.03.003 |
| format | Article |
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We assessed whether the impact of each risk factor differed between CHD and stroke mortality in Asians. Methods In total, 104 910 subjects aged 40–79 years without histories of cancer, CHD and stroke at baseline were followed between 1988 and 2009. Competing-risks analysis was used to test for differences in the associations of each risk factor with two endpoints (CHD and stroke). Population attributable fractions (PAFs) were also calculated for these endpoints to estimate the population impact of each risk factor. Results During a median 19.1-year follow-up, 1554 died from CHD and 3163 from stroke. The association of hypertension with CHD was similar to that with stroke in terms of the magnitude and direction (multivariable-adjusted hazard ratio for CHD: 1.63 vs. stroke: 1.73 in men and 1.70 vs. 1.66 in women). Conversely, the magnitude of these associations differed for smoking (CHD: 1.95 vs. stroke: 1.23 in men and 2.45 vs. 1.35 in women) and diabetes (1.49 vs. 1.09 in men and 2.08 vs. 1.39 in women). The highest PAF for CHD was caused by smoking in men and by hypertension in women; that for stroke was caused by hypertension in both sexes. Conclusions Hypertension associations and PAFs were consistent between CHD and stroke, but not for other risk factors. These findings may be useful to optimize public health intervention strategies.</description><identifier>ISSN: 0021-9150</identifier><identifier>EISSN: 1879-1484</identifier><identifier>DOI: 10.1016/j.atherosclerosis.2017.03.003</identifier><identifier>PMID: 28292514</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Adult ; Aged ; Cardiovascular ; Cardiovascular disease ; Cause of Death ; Comorbidity ; Coronary Disease - diagnosis ; Coronary Disease - epidemiology ; Coronary Disease - mortality ; Coronary heart disease ; Diabetes Mellitus - diagnosis ; Diabetes Mellitus - epidemiology ; Epidemiology ; Female ; Humans ; Hypertension - diagnosis ; Hypertension - epidemiology ; Japan - epidemiology ; Male ; Middle Aged ; Mortality ; Prognosis ; Proportional Hazards Models ; Prospective Studies ; Risk Assessment ; Risk Factors ; Sex Factors ; Smoking - adverse effects ; Smoking - epidemiology ; Socioeconomic Factors ; Stroke ; Stroke - diagnosis ; Stroke - epidemiology ; Stroke - mortality ; Time Factors</subject><ispartof>Atherosclerosis, 2017-06, Vol.261, p.124-130</ispartof><rights>2017 Elsevier B.V.</rights><rights>Copyright © 2017 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c528t-b670baf6292d2a55f4c548c9d75f4650fc65f75e7c2a906209d2f8c832ce39a13</citedby><cites>FETCH-LOGICAL-c528t-b670baf6292d2a55f4c548c9d75f4650fc65f75e7c2a906209d2f8c832ce39a13</cites><orcidid>0000-0002-6220-9251</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.atherosclerosis.2017.03.003$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28292514$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Matsunaga, Masaaki</creatorcontrib><creatorcontrib>Yatsuya, Hiroshi</creatorcontrib><creatorcontrib>Iso, Hiroyasu</creatorcontrib><creatorcontrib>Yamashita, Kentaro</creatorcontrib><creatorcontrib>Li, Yuanying</creatorcontrib><creatorcontrib>Yamagishi, Kazumasa</creatorcontrib><creatorcontrib>Tanabe, Naohito</creatorcontrib><creatorcontrib>Wada, Yasuhiko</creatorcontrib><creatorcontrib>Wang, Chaochen</creatorcontrib><creatorcontrib>Ota, Atsuhiko</creatorcontrib><creatorcontrib>Tamakoshi, Koji</creatorcontrib><creatorcontrib>Tamakoshi, Akiko</creatorcontrib><creatorcontrib>The JACC Study Group</creatorcontrib><creatorcontrib>JACC Study Group</creatorcontrib><title>Similarities and differences between coronary heart disease and stroke in the associations with cardiovascular risk factors: The Japan collaborative cohort study</title><title>Atherosclerosis</title><addtitle>Atherosclerosis</addtitle><description>Abstract Background and aims Coronary heart disease (CHD) and stroke have common risk factors, but some of these differ in the magnitude or direction of associations between CHD and stroke. We assessed whether the impact of each risk factor differed between CHD and stroke mortality in Asians. Methods In total, 104 910 subjects aged 40–79 years without histories of cancer, CHD and stroke at baseline were followed between 1988 and 2009. Competing-risks analysis was used to test for differences in the associations of each risk factor with two endpoints (CHD and stroke). Population attributable fractions (PAFs) were also calculated for these endpoints to estimate the population impact of each risk factor. Results During a median 19.1-year follow-up, 1554 died from CHD and 3163 from stroke. The association of hypertension with CHD was similar to that with stroke in terms of the magnitude and direction (multivariable-adjusted hazard ratio for CHD: 1.63 vs. stroke: 1.73 in men and 1.70 vs. 1.66 in women). Conversely, the magnitude of these associations differed for smoking (CHD: 1.95 vs. stroke: 1.23 in men and 2.45 vs. 1.35 in women) and diabetes (1.49 vs. 1.09 in men and 2.08 vs. 1.39 in women). The highest PAF for CHD was caused by smoking in men and by hypertension in women; that for stroke was caused by hypertension in both sexes. Conclusions Hypertension associations and PAFs were consistent between CHD and stroke, but not for other risk factors. These findings may be useful to optimize public health intervention strategies.</description><subject>Adult</subject><subject>Aged</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Cause of Death</subject><subject>Comorbidity</subject><subject>Coronary Disease - diagnosis</subject><subject>Coronary Disease - epidemiology</subject><subject>Coronary Disease - mortality</subject><subject>Coronary heart disease</subject><subject>Diabetes Mellitus - diagnosis</subject><subject>Diabetes Mellitus - epidemiology</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Hypertension - diagnosis</subject><subject>Hypertension - epidemiology</subject><subject>Japan - epidemiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Prognosis</subject><subject>Proportional Hazards Models</subject><subject>Prospective Studies</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Smoking - adverse effects</subject><subject>Smoking - epidemiology</subject><subject>Socioeconomic Factors</subject><subject>Stroke</subject><subject>Stroke - diagnosis</subject><subject>Stroke - epidemiology</subject><subject>Stroke - mortality</subject><subject>Time Factors</subject><issn>0021-9150</issn><issn>1879-1484</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNUk1v1DAQtRCIbgt_AfmCxCVh7MT5QAIJVdCCKnFokbhZjjPRejcbLx5nq_05_FMctnDoiYvHI703b2beMPZaQC5AVG83uYlrDJ7suLyOcgmizqHIAYonbCWaus1E2ZRP2QpAiqwVCs7YOdEGAMpaNM_ZmWxkK5UoV-zXrdu50QQXHRI3U897NwwYcLIp7zDeI07c-uAnE458jSbEBCE0hH_gFIPfIncTT21xQ-StM9H5ifi9i2tuTeidPxiyc5LhwdGWD8ZGH-gdv0uUr2ZvFoVxNJ0PiXrAlK190qE498cX7NlgRsKXD_GCff_86e7yOrv5dvXl8uNNZpVsYtZVNXRmqNJgvTRKDaVVZWPbvk7fSsFgKzXUCmsrTQuVhLaXQ2ObQlosWiOKC_bmVHcf_M8ZKeqdI4uprQn9TDottm6UqGSdoO9PUJscoICD3ge3S_vRAvTikt7oRy7pxSUNhU4uJf6rB6m522H_j_3XlgS4OgEwDXxwGDRZt1jSu4A26t67_5b68KiSHd3krBm3eETa-DlMaataaJIa9O1yMsvFiLoAaIsfxW-6e8bl</recordid><startdate>20170601</startdate><enddate>20170601</enddate><creator>Matsunaga, Masaaki</creator><creator>Yatsuya, Hiroshi</creator><creator>Iso, Hiroyasu</creator><creator>Yamashita, Kentaro</creator><creator>Li, Yuanying</creator><creator>Yamagishi, Kazumasa</creator><creator>Tanabe, Naohito</creator><creator>Wada, Yasuhiko</creator><creator>Wang, Chaochen</creator><creator>Ota, Atsuhiko</creator><creator>Tamakoshi, Koji</creator><creator>Tamakoshi, Akiko</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6220-9251</orcidid></search><sort><creationdate>20170601</creationdate><title>Similarities and differences between coronary heart disease and stroke in the associations with cardiovascular risk factors: The Japan collaborative cohort study</title><author>Matsunaga, Masaaki ; Yatsuya, Hiroshi ; Iso, Hiroyasu ; Yamashita, Kentaro ; Li, Yuanying ; Yamagishi, Kazumasa ; Tanabe, Naohito ; Wada, Yasuhiko ; Wang, Chaochen ; Ota, Atsuhiko ; Tamakoshi, Koji ; Tamakoshi, Akiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c528t-b670baf6292d2a55f4c548c9d75f4650fc65f75e7c2a906209d2f8c832ce39a13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Cardiovascular</topic><topic>Cardiovascular disease</topic><topic>Cause of Death</topic><topic>Comorbidity</topic><topic>Coronary Disease - diagnosis</topic><topic>Coronary Disease - epidemiology</topic><topic>Coronary Disease - mortality</topic><topic>Coronary heart disease</topic><topic>Diabetes Mellitus - diagnosis</topic><topic>Diabetes Mellitus - epidemiology</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Hypertension - diagnosis</topic><topic>Hypertension - epidemiology</topic><topic>Japan - epidemiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Prognosis</topic><topic>Proportional Hazards Models</topic><topic>Prospective Studies</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>Smoking - adverse effects</topic><topic>Smoking - epidemiology</topic><topic>Socioeconomic Factors</topic><topic>Stroke</topic><topic>Stroke - diagnosis</topic><topic>Stroke - epidemiology</topic><topic>Stroke - mortality</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Matsunaga, Masaaki</creatorcontrib><creatorcontrib>Yatsuya, Hiroshi</creatorcontrib><creatorcontrib>Iso, Hiroyasu</creatorcontrib><creatorcontrib>Yamashita, Kentaro</creatorcontrib><creatorcontrib>Li, Yuanying</creatorcontrib><creatorcontrib>Yamagishi, Kazumasa</creatorcontrib><creatorcontrib>Tanabe, Naohito</creatorcontrib><creatorcontrib>Wada, Yasuhiko</creatorcontrib><creatorcontrib>Wang, Chaochen</creatorcontrib><creatorcontrib>Ota, Atsuhiko</creatorcontrib><creatorcontrib>Tamakoshi, Koji</creatorcontrib><creatorcontrib>Tamakoshi, Akiko</creatorcontrib><creatorcontrib>The JACC Study Group</creatorcontrib><creatorcontrib>JACC Study Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Atherosclerosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Matsunaga, Masaaki</au><au>Yatsuya, Hiroshi</au><au>Iso, Hiroyasu</au><au>Yamashita, Kentaro</au><au>Li, Yuanying</au><au>Yamagishi, Kazumasa</au><au>Tanabe, Naohito</au><au>Wada, Yasuhiko</au><au>Wang, Chaochen</au><au>Ota, Atsuhiko</au><au>Tamakoshi, Koji</au><au>Tamakoshi, Akiko</au><aucorp>The JACC Study Group</aucorp><aucorp>JACC Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Similarities and differences between coronary heart disease and stroke in the associations with cardiovascular risk factors: The Japan collaborative cohort study</atitle><jtitle>Atherosclerosis</jtitle><addtitle>Atherosclerosis</addtitle><date>2017-06-01</date><risdate>2017</risdate><volume>261</volume><spage>124</spage><epage>130</epage><pages>124-130</pages><issn>0021-9150</issn><eissn>1879-1484</eissn><abstract>Abstract Background and aims Coronary heart disease (CHD) and stroke have common risk factors, but some of these differ in the magnitude or direction of associations between CHD and stroke. We assessed whether the impact of each risk factor differed between CHD and stroke mortality in Asians. Methods In total, 104 910 subjects aged 40–79 years without histories of cancer, CHD and stroke at baseline were followed between 1988 and 2009. Competing-risks analysis was used to test for differences in the associations of each risk factor with two endpoints (CHD and stroke). Population attributable fractions (PAFs) were also calculated for these endpoints to estimate the population impact of each risk factor. Results During a median 19.1-year follow-up, 1554 died from CHD and 3163 from stroke. The association of hypertension with CHD was similar to that with stroke in terms of the magnitude and direction (multivariable-adjusted hazard ratio for CHD: 1.63 vs. stroke: 1.73 in men and 1.70 vs. 1.66 in women). Conversely, the magnitude of these associations differed for smoking (CHD: 1.95 vs. stroke: 1.23 in men and 2.45 vs. 1.35 in women) and diabetes (1.49 vs. 1.09 in men and 2.08 vs. 1.39 in women). The highest PAF for CHD was caused by smoking in men and by hypertension in women; that for stroke was caused by hypertension in both sexes. Conclusions Hypertension associations and PAFs were consistent between CHD and stroke, but not for other risk factors. These findings may be useful to optimize public health intervention strategies.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>28292514</pmid><doi>10.1016/j.atherosclerosis.2017.03.003</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-6220-9251</orcidid></addata></record> |
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| subjects | Adult Aged Cardiovascular Cardiovascular disease Cause of Death Comorbidity Coronary Disease - diagnosis Coronary Disease - epidemiology Coronary Disease - mortality Coronary heart disease Diabetes Mellitus - diagnosis Diabetes Mellitus - epidemiology Epidemiology Female Humans Hypertension - diagnosis Hypertension - epidemiology Japan - epidemiology Male Middle Aged Mortality Prognosis Proportional Hazards Models Prospective Studies Risk Assessment Risk Factors Sex Factors Smoking - adverse effects Smoking - epidemiology Socioeconomic Factors Stroke Stroke - diagnosis Stroke - epidemiology Stroke - mortality Time Factors |
| title | Similarities and differences between coronary heart disease and stroke in the associations with cardiovascular risk factors: The Japan collaborative cohort study |
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