Association of IL12B risk haplotype and lack of interaction with HLA-Cw6 among the psoriasis patients in India

Psoriasis is a complex multifactorial chronic inflammatory skin disorder involving both genetic and environmental susceptibility factors. It is strongly associated with HLA-Cw6, but several studies suggested that further genetic factors may confer additional risk. We investigated the association of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of human genetics 2017-03, Vol.62 (3), p.389-395
Hauptverfasser:	Chandra, Aditi, Senapati, Swapan, Ghosh, Saurabh, Chatterjee, Gobinda, Chatterjee, Raghunath
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Adult Alleles Case-Control Studies Epistasis Epistasis, Genetic Female Gene Expression Gene Frequency Genetic factors Genetic Predisposition to Disease Haplotypes Histocompatibility antigen HLA HLA-C Antigens - genetics HLA-C Antigens - immunology Humans IL12B protein India Interleukin 1 Interleukin 12 Interleukin-12 Subunit p40 - genetics Interleukin-12 Subunit p40 - immunology Male Middle Aged Odds Ratio Polymorphism, Single Nucleotide Psoriasis Psoriasis - genetics Psoriasis - immunology Psoriasis - pathology Risk Single-nucleotide polymorphism Skin - immunology Skin - metabolism Skin - pathology Skin diseases Susceptibility Transcription
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!