WNT1 Gene from WNT Signaling Pathway Is a Direct Target of miR-122 in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is an invasive form of hepatic cancer arising from the accumulation of multiple genetic alterations. In this study, the causal role of disturbed canonical Wnt/β-catenin pathway was approved, and some of HCC-driven important gene candidates were determined. MicroRNAs (m...

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Veröffentlicht in:	Applied biochemistry and biotechnology 2017-03, Vol.181 (3), p.884-897
Hauptverfasser:	Ahsani, Zeinab, Mohammadi-Yeganeh, Samira, Kia, Vahid, Karimkhanloo, Hamzeh, Zarghami, Nosratollah, Paryan, Mahdi
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Bioaccumulation Biochemistry Bioinformatics Biotechnology Cancer Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Chemistry Chemistry and Materials Science Gene Expression Regulation, Neoplastic Genetics Hep G2 Cells Hepatology Humans Liver Neoplasms - genetics Liver Neoplasms - metabolism MicroRNAs - genetics MicroRNAs - metabolism RNA, Neoplasm - genetics RNA, Neoplasm - metabolism Signal transduction Wnt Signaling Pathway Wnt1 Protein - biosynthesis Wnt1 Protein - genetics
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