Lipoprotein lipase liberates free fatty acids to inhibit HCV infection and prevent hepatic lipid accumulation

Lipoprotein lipase (LPL) has been identified as an anti‐hepatitis C virus (HCV) host factor, but the cellular mechanism remains elusive. Here, we investigated the cellular mechanism of LPL involving in anti‐HCV. The functional activation of peroxisome proliferator‐activated receptor (PPAR) α signal...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cellular microbiology 2017-04, Vol.19 (4), p.np-n/a
Hauptverfasser:	Sun, Hung‐Yu, Lin, Chun‐Chieh, Tsai, Pei‐Ju, Tsai, Wei‐Jen, Lee, Jin‐Ching, Tsao, Chiung‐Wen, Cheng, Pin‐Nan, Wu, I‐Chin, Chiu, Yen‐Cheng, Chang, Ting‐Tsung, Young, Kung‐Chia
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Activation Albumin Albumins Alpha rays Animals Apolipoproteins CD36 CD36 antigen CD36 Antigens - metabolism Cell Line, Tumor Core protein Enzymatic activity Fasting Fatty acids Fatty Acids, Nonesterified - metabolism free fatty acids Gene Expression Genes Hepacivirus - physiology Hepatitis Hepatitis C Hepatitis C - metabolism Hepatitis C - virology Hepatitis C virus Hepatocytes Hepatocytes - enzymology Hepatocytes - virology Host-Pathogen Interactions Humans Immunity, Innate Lipase Lipids Lipolysis Lipoprotein lipase Lipoprotein Lipase - physiology Lipoproteins Lipoproteins, VLDL - metabolism Liver Liver - enzymology Liver - virology Male Mice, Inbred C57BL Mice, Transgenic MicroRNAs - genetics MicroRNAs - metabolism Modulators Nuclear transport Oxidation Peroxisome proliferator-activated receptors PPAR alpha - metabolism PPARα Rodents Steatosis Transcription Transgenic animals Transgenic mice Translocase Viral Core Proteins - physiology Virions Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!