The C‐terminus of amelogenin enhances osteogenic differentiation of human cementoblast lineage cells

Background and Objectives Amelogenin proteins are the major constituent of developing extracellular enamel matrix and are believed to have an exclusively epithelial origin. Recent studies have suggested that amelogenins might induce the differentiation and maturation of various cells, including ceme...

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Veröffentlicht in:	Journal of periodontal research 2017-04, Vol.52 (2), p.218-224
Hauptverfasser:	Kunimatsu, R., Yoshimi, Y., Hirose, N., Awada, T., Miyauchi, M., Takata, T., Li, W., Zhu, L., Denbesten, P.K., Tanimoto, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline phosphatase Amelogenin - pharmacology C-Terminus Calcium Catalytic Domain Cell Differentiation - drug effects Cell Differentiation - physiology Cell Line cementoblast Dental Cementum - drug effects Dental Cementum - physiology Dental enamel Dentistry Dose-Response Relationship, Drug enamel proteins Humans Mineralization mRNA N-Terminus Osteogenesis - drug effects Osteogenesis - physiology Peptide Fragments - pharmacology Peptides Periodontics Polymerase chain reaction Regeneration
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