Early life stress experience may blunt hypothalamic leptin signalling

The aim of this study was to investigate whether neonatal maternal separation (MS) – chronic stress experience in early life – affects the anorectic efficacy of leptin in the offspring at adolescence. Sprague–Dawley pups were separated from the dam daily for 3 h during postnatal day 1–14 or left und...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of biosciences 2017-03, Vol.42 (1), p.131-138
Hauptverfasser:	Lee, J H, Yoo, S B, Kim, J Y, Lee, J Y, Kim, B T, Park, K, Jahng, J W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Arcuate Nucleus of Hypothalamus - metabolism Biology Biomedical and Life Sciences Biomedicine Body Weight Cell Biology Child development Diet Eating Hypothalamus - metabolism Leptin - administration & dosage Leptin - metabolism Life Sciences Male Microbiology Neonatal care Offspring Plant Sciences Protein Tyrosine Phosphatase, Non-Receptor Type 1 - biosynthesis Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics Rats Rats, Sprague-Dawley Signal Transduction - genetics STAT3 Transcription Factor - biosynthesis STAT3 Transcription Factor - genetics Stress response Stress, Psychological - genetics Stress, Psychological - metabolism Zoology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!