Serum AGR2 as a useful biomarker for pituitary adenomas
Highlights • The serum AGR2 level was higher in PA patients than that in normal control. • The serum AGR2 level was higher in PA patients than that with other sellar lesions. • There is no significant difference of AGR2 level in different PA subtypes. • The detection of serum AGR2 levels by ELISA ha...
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| Veröffentlicht in: | Clinical neurology and neurosurgery 2017-03, Vol.154, p.19-22 |
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| container_title | Clinical neurology and neurosurgery |
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| creator | Tohti, Mamatemin Li, Junyang Tang, Chao Wen, Guodao Abdujilil, Abdukeyum Yizim, Parhat Ma, Chiyuan |
| description | Highlights • The serum AGR2 level was higher in PA patients than that in normal control. • The serum AGR2 level was higher in PA patients than that with other sellar lesions. • There is no significant difference of AGR2 level in different PA subtypes. • The detection of serum AGR2 levels by ELISA has high diagnostic accuracy. • The larger the tumor size is, the lower the mean serum level of AGR2. |
| doi_str_mv | 10.1016/j.clineuro.2017.01.004 |
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All rights reserved.</rights><rights>Copyright Elsevier Limited 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484t-f45b1b1c2095b143be06538bc1d27defc81a845b26ea3fd29fce7193e65221d73</citedby><cites>FETCH-LOGICAL-c484t-f45b1b1c2095b143be06538bc1d27defc81a845b26ea3fd29fce7193e65221d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1872561963?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976,64364,64366,64368,72218</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28092730$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tohti, Mamatemin</creatorcontrib><creatorcontrib>Li, Junyang</creatorcontrib><creatorcontrib>Tang, Chao</creatorcontrib><creatorcontrib>Wen, Guodao</creatorcontrib><creatorcontrib>Abdujilil, Abdukeyum</creatorcontrib><creatorcontrib>Yizim, Parhat</creatorcontrib><creatorcontrib>Ma, Chiyuan</creatorcontrib><title>Serum AGR2 as a useful biomarker for pituitary adenomas</title><title>Clinical neurology and neurosurgery</title><addtitle>Clin Neurol Neurosurg</addtitle><description>Highlights • The serum AGR2 level was higher in PA patients than that in normal control. • The serum AGR2 level was higher in PA patients than that with other sellar lesions. • There is no significant difference of AGR2 level in different PA subtypes. • The detection of serum AGR2 levels by ELISA has high diagnostic accuracy. • The larger the tumor size is, the lower the mean serum level of AGR2.</description><subject>Adenoma - blood</subject><subject>Adenoma - pathology</subject><subject>Anterior gradient 2</subject><subject>Biomarkers</subject><subject>Biomarkers, Tumor - blood</subject><subject>Breast cancer</subject><subject>Cysts</subject><subject>Diagnosis</subject><subject>Female</subject><subject>Females</subject><subject>Humans</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Metastasis</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Pituitary adenoma</subject><subject>Pituitary Neoplasms - blood</subject><subject>Pituitary Neoplasms - pathology</subject><subject>Proteins - metabolism</subject><subject>Sensitivity and Specificity</subject><subject>Serum biomarker</subject><subject>Statistical analysis</subject><subject>Studies</subject><subject>Tumors</subject><issn>0303-8467</issn><issn>1872-6968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkk9r3DAQxUVJSLZJvkIw9JKL3dEfS_KlJIQ2LQQCTXMWsjwGbbz2RrIC--0rs0kDuaQnDeg3b3jzhpBzChUFKr-uKzf4EVOYKgZUVUArAPGJrKhWrJSN1AdkBRx4qYVUx-RzjGsA4FzqI3LMNDRMcVgRdY8hbYqrm9-ssLGwRYrYp6Fo_bSx4RFD0U-h2Po5-dmGXWE7HPNPPCWHvR0inr28J-Thx_c_1z_L27ubX9dXt6UTWsxlL-qWttQxaHIheIsga65bRzumOuydplZnhkm0vO9Y0ztUtOEoa8Zop_gJudjrbsP0lDDOZuOjw2GwI04pmmxXacFEXf8HKmktuNJNRr-8Q9dTCmM2sgiyWtJG8kzJPeXCFGPA3myDz1vZGQpmScGszWsKZknBADU5hdx4_iKf2g12_9pe156Byz2AeXXPHoOJzuPosPMB3Wy6yX8849s7iQXzzg6PuMP45sdEZsDcL7ewnALN83N_zf8CflGuNA</recordid><startdate>20170301</startdate><enddate>20170301</enddate><creator>Tohti, Mamatemin</creator><creator>Li, Junyang</creator><creator>Tang, Chao</creator><creator>Wen, Guodao</creator><creator>Abdujilil, Abdukeyum</creator><creator>Yizim, Parhat</creator><creator>Ma, Chiyuan</creator><general>Elsevier B.V</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20170301</creationdate><title>Serum AGR2 as a useful biomarker for pituitary adenomas</title><author>Tohti, Mamatemin ; Li, Junyang ; Tang, Chao ; Wen, Guodao ; Abdujilil, Abdukeyum ; Yizim, Parhat ; Ma, Chiyuan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-f45b1b1c2095b143be06538bc1d27defc81a845b26ea3fd29fce7193e65221d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adenoma - blood</topic><topic>Adenoma - pathology</topic><topic>Anterior gradient 2</topic><topic>Biomarkers</topic><topic>Biomarkers, Tumor - blood</topic><topic>Breast cancer</topic><topic>Cysts</topic><topic>Diagnosis</topic><topic>Female</topic><topic>Females</topic><topic>Humans</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Metastasis</topic><topic>Neurology</topic><topic>Neurosurgery</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Pituitary adenoma</topic><topic>Pituitary Neoplasms - blood</topic><topic>Pituitary Neoplasms - pathology</topic><topic>Proteins - metabolism</topic><topic>Sensitivity and Specificity</topic><topic>Serum biomarker</topic><topic>Statistical analysis</topic><topic>Studies</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tohti, Mamatemin</creatorcontrib><creatorcontrib>Li, Junyang</creatorcontrib><creatorcontrib>Tang, Chao</creatorcontrib><creatorcontrib>Wen, Guodao</creatorcontrib><creatorcontrib>Abdujilil, Abdukeyum</creatorcontrib><creatorcontrib>Yizim, Parhat</creatorcontrib><creatorcontrib>Ma, Chiyuan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical neurology and neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tohti, Mamatemin</au><au>Li, Junyang</au><au>Tang, Chao</au><au>Wen, Guodao</au><au>Abdujilil, Abdukeyum</au><au>Yizim, Parhat</au><au>Ma, Chiyuan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serum AGR2 as a useful biomarker for pituitary adenomas</atitle><jtitle>Clinical neurology and neurosurgery</jtitle><addtitle>Clin Neurol Neurosurg</addtitle><date>2017-03-01</date><risdate>2017</risdate><volume>154</volume><spage>19</spage><epage>22</epage><pages>19-22</pages><issn>0303-8467</issn><eissn>1872-6968</eissn><coden>CNNSBV</coden><abstract>Highlights • The serum AGR2 level was higher in PA patients than that in normal control. • The serum AGR2 level was higher in PA patients than that with other sellar lesions. • There is no significant difference of AGR2 level in different PA subtypes. • The detection of serum AGR2 levels by ELISA has high diagnostic accuracy. • The larger the tumor size is, the lower the mean serum level of AGR2.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>28092730</pmid><doi>10.1016/j.clineuro.2017.01.004</doi><tpages>4</tpages></addata></record> |
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| subjects | Adenoma - blood Adenoma - pathology Anterior gradient 2 Biomarkers Biomarkers, Tumor - blood Breast cancer Cysts Diagnosis Female Females Humans Male Medical prognosis Metastasis Neurology Neurosurgery NMR Nuclear magnetic resonance Pituitary adenoma Pituitary Neoplasms - blood Pituitary Neoplasms - pathology Proteins - metabolism Sensitivity and Specificity Serum biomarker Statistical analysis Studies Tumors |
| title | Serum AGR2 as a useful biomarker for pituitary adenomas |
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