Magnetic resonance imaging appearance of soft-tissue metastases: our experience at an orthopedic oncology center
Objective To assess the prevalence and magnetic resonance imaging appearance of metastasis presenting as a soft-tissue mass. Materials and methods A retrospective chart review was performed on 51 patients who presented to an orthopedic oncology center with soft-tissue masses, with a histology-proven...
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| Veröffentlicht in: | Skeletal radiology 2017-04, Vol.46 (4), p.513-521 |
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| creator | Sammon, Jennifer Jain, Abhishek Bleakney, Robert Mohankumar, Rakesh |
| description | Objective
To assess the prevalence and magnetic resonance imaging appearance of metastasis presenting as a soft-tissue mass.
Materials and methods
A retrospective chart review was performed on 51 patients who presented to an orthopedic oncology center with soft-tissue masses, with a histology-proven diagnosis of soft-tissue metastasis, over a 14-year period. Their magnetic resonance imaging, primary origin, and follow-up have been assessed.
Results
Soft-tissue metastasis was identified in patients ranging from 18 to 85 years old. Most (80%) of the masses were located deep to the deep fascia. In our cohort of patients, melanoma was the most common primary malignancy contributing to soft-tissue metastasis (21.8%). Among soft-tissue metastasis from solid organs, breast and lung were the most frequent (9.1% each). Five patients had soft-tissue metastases from an unknown primary.
Conclusion
Imaging diagnosis of soft-tissue metastases is challenging as it can demonstrate imaging appearances similar to primary soft-tissue sarcoma. The presence of a known malignancy may not be evident in everyone, and even if available, histopathology will be necessary for diagnosis if this is the only site of recurrence/metastasis to differentiate from a primary soft-tissue sarcoma. Moreover, soft-tissue metastasis may be the initial presentation of a malignancy. Primary malignancies with soft-tissue metastasis carry a poor prognosis; hence, prompt diagnosis and management in essential. |
| doi_str_mv | 10.1007/s00256-017-2582-0 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1877838793</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A731035773</galeid><sourcerecordid>A731035773</sourcerecordid><originalsourceid>FETCH-LOGICAL-c472t-30973a57e9734154e7547e3fc45df54c76cc5a6d1881249eec9eac659a39ae5b3</originalsourceid><addsrcrecordid>eNqNkk9rFjEQxoNY7NvqB_AiAS9etuZ_st5K0SpUemnPIc3Orlt2kzXJgv32Zvu-ioqCJDAw-c3DzORB6CUlZ5QQ_TYTwqRqCNUNk4Y15AnaUcFZw6iiT9GOcCUaxoU5Ric535MKaqmeoWNmqCGtFDu0fHZDgDJ6nCDH4IIHPM5uGMOA3bKAS4-p2OMc-9KUMecV8AzF5Xohv8NxTRi-LZBG2EhXsAs4pvIlLtBV3Rh8nOLwgD2EAuk5OurdlOHFIZ6i2w_vby4-NlfXl58uzq8aLzQrDSet5k5qqEFQKUBLoYH3Xsiul8Jr5b10qqPGUCZaAN-C80q2jrcO5B0_RW_2ukuKX1fIxc5j9jBNLkBcs6VGa8ONbvl_oEqpui1iKvr6D_S-zh_qIBvV1gWrR8EDNbgJ7Bj6WJLzm6g915wSLrXeqLO_UPV0MI8-BujHmv-tgO4LfIo5J-jtkupfpQdLid0MYfeGsLUNuxnCklrz6tDwejdD97PihwMqwPZArk9hgPTLRP9U_Q4Gqb8u</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1869017693</pqid></control><display><type>article</type><title>Magnetic resonance imaging appearance of soft-tissue metastases: our experience at an orthopedic oncology center</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Sammon, Jennifer ; Jain, Abhishek ; Bleakney, Robert ; Mohankumar, Rakesh</creator><creatorcontrib>Sammon, Jennifer ; Jain, Abhishek ; Bleakney, Robert ; Mohankumar, Rakesh</creatorcontrib><description>Objective
To assess the prevalence and magnetic resonance imaging appearance of metastasis presenting as a soft-tissue mass.
Materials and methods
A retrospective chart review was performed on 51 patients who presented to an orthopedic oncology center with soft-tissue masses, with a histology-proven diagnosis of soft-tissue metastasis, over a 14-year period. Their magnetic resonance imaging, primary origin, and follow-up have been assessed.
Results
Soft-tissue metastasis was identified in patients ranging from 18 to 85 years old. Most (80%) of the masses were located deep to the deep fascia. In our cohort of patients, melanoma was the most common primary malignancy contributing to soft-tissue metastasis (21.8%). Among soft-tissue metastasis from solid organs, breast and lung were the most frequent (9.1% each). Five patients had soft-tissue metastases from an unknown primary.
Conclusion
Imaging diagnosis of soft-tissue metastases is challenging as it can demonstrate imaging appearances similar to primary soft-tissue sarcoma. The presence of a known malignancy may not be evident in everyone, and even if available, histopathology will be necessary for diagnosis if this is the only site of recurrence/metastasis to differentiate from a primary soft-tissue sarcoma. Moreover, soft-tissue metastasis may be the initial presentation of a malignancy. Primary malignancies with soft-tissue metastasis carry a poor prognosis; hence, prompt diagnosis and management in essential.</description><identifier>ISSN: 0364-2348</identifier><identifier>EISSN: 1432-2161</identifier><identifier>DOI: 10.1007/s00256-017-2582-0</identifier><identifier>PMID: 28180954</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Imaging ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Male ; Medical imaging equipment ; Medicine ; Medicine & Public Health ; Melanoma ; Metastasis ; Middle Aged ; Nuclear Medicine ; Orthopedics ; Pathology ; Prevalence ; Radiology ; Retrospective Studies ; Sarcoma ; Scientific Article ; Soft Tissue Neoplasms - diagnostic imaging ; Soft Tissue Neoplasms - epidemiology ; Soft Tissue Neoplasms - secondary ; Young Adult</subject><ispartof>Skeletal radiology, 2017-04, Vol.46 (4), p.513-521</ispartof><rights>ISS 2017</rights><rights>COPYRIGHT 2017 Springer</rights><rights>Skeletal Radiology is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-30973a57e9734154e7547e3fc45df54c76cc5a6d1881249eec9eac659a39ae5b3</citedby><cites>FETCH-LOGICAL-c472t-30973a57e9734154e7547e3fc45df54c76cc5a6d1881249eec9eac659a39ae5b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00256-017-2582-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00256-017-2582-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,27929,27930,41493,42562,51324</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28180954$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sammon, Jennifer</creatorcontrib><creatorcontrib>Jain, Abhishek</creatorcontrib><creatorcontrib>Bleakney, Robert</creatorcontrib><creatorcontrib>Mohankumar, Rakesh</creatorcontrib><title>Magnetic resonance imaging appearance of soft-tissue metastases: our experience at an orthopedic oncology center</title><title>Skeletal radiology</title><addtitle>Skeletal Radiol</addtitle><addtitle>Skeletal Radiol</addtitle><description>Objective
To assess the prevalence and magnetic resonance imaging appearance of metastasis presenting as a soft-tissue mass.
Materials and methods
A retrospective chart review was performed on 51 patients who presented to an orthopedic oncology center with soft-tissue masses, with a histology-proven diagnosis of soft-tissue metastasis, over a 14-year period. Their magnetic resonance imaging, primary origin, and follow-up have been assessed.
Results
Soft-tissue metastasis was identified in patients ranging from 18 to 85 years old. Most (80%) of the masses were located deep to the deep fascia. In our cohort of patients, melanoma was the most common primary malignancy contributing to soft-tissue metastasis (21.8%). Among soft-tissue metastasis from solid organs, breast and lung were the most frequent (9.1% each). Five patients had soft-tissue metastases from an unknown primary.
Conclusion
Imaging diagnosis of soft-tissue metastases is challenging as it can demonstrate imaging appearances similar to primary soft-tissue sarcoma. The presence of a known malignancy may not be evident in everyone, and even if available, histopathology will be necessary for diagnosis if this is the only site of recurrence/metastasis to differentiate from a primary soft-tissue sarcoma. Moreover, soft-tissue metastasis may be the initial presentation of a malignancy. Primary malignancies with soft-tissue metastasis carry a poor prognosis; hence, prompt diagnosis and management in essential.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Female</subject><subject>Humans</subject><subject>Imaging</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Medical imaging equipment</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Melanoma</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Nuclear Medicine</subject><subject>Orthopedics</subject><subject>Pathology</subject><subject>Prevalence</subject><subject>Radiology</subject><subject>Retrospective Studies</subject><subject>Sarcoma</subject><subject>Scientific Article</subject><subject>Soft Tissue Neoplasms - diagnostic imaging</subject><subject>Soft Tissue Neoplasms - epidemiology</subject><subject>Soft Tissue Neoplasms - secondary</subject><subject>Young Adult</subject><issn>0364-2348</issn><issn>1432-2161</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkk9rFjEQxoNY7NvqB_AiAS9etuZ_st5K0SpUemnPIc3Orlt2kzXJgv32Zvu-ioqCJDAw-c3DzORB6CUlZ5QQ_TYTwqRqCNUNk4Y15AnaUcFZw6iiT9GOcCUaxoU5Ric535MKaqmeoWNmqCGtFDu0fHZDgDJ6nCDH4IIHPM5uGMOA3bKAS4-p2OMc-9KUMecV8AzF5Xohv8NxTRi-LZBG2EhXsAs4pvIlLtBV3Rh8nOLwgD2EAuk5OurdlOHFIZ6i2w_vby4-NlfXl58uzq8aLzQrDSet5k5qqEFQKUBLoYH3Xsiul8Jr5b10qqPGUCZaAN-C80q2jrcO5B0_RW_2ukuKX1fIxc5j9jBNLkBcs6VGa8ONbvl_oEqpui1iKvr6D_S-zh_qIBvV1gWrR8EDNbgJ7Bj6WJLzm6g915wSLrXeqLO_UPV0MI8-BujHmv-tgO4LfIo5J-jtkupfpQdLid0MYfeGsLUNuxnCklrz6tDwejdD97PihwMqwPZArk9hgPTLRP9U_Q4Gqb8u</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>Sammon, Jennifer</creator><creator>Jain, Abhishek</creator><creator>Bleakney, Robert</creator><creator>Mohankumar, Rakesh</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20170401</creationdate><title>Magnetic resonance imaging appearance of soft-tissue metastases: our experience at an orthopedic oncology center</title><author>Sammon, Jennifer ; Jain, Abhishek ; Bleakney, Robert ; Mohankumar, Rakesh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-30973a57e9734154e7547e3fc45df54c76cc5a6d1881249eec9eac659a39ae5b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Female</topic><topic>Humans</topic><topic>Imaging</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Medical imaging equipment</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Melanoma</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Nuclear Medicine</topic><topic>Orthopedics</topic><topic>Pathology</topic><topic>Prevalence</topic><topic>Radiology</topic><topic>Retrospective Studies</topic><topic>Sarcoma</topic><topic>Scientific Article</topic><topic>Soft Tissue Neoplasms - diagnostic imaging</topic><topic>Soft Tissue Neoplasms - epidemiology</topic><topic>Soft Tissue Neoplasms - secondary</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sammon, Jennifer</creatorcontrib><creatorcontrib>Jain, Abhishek</creatorcontrib><creatorcontrib>Bleakney, Robert</creatorcontrib><creatorcontrib>Mohankumar, Rakesh</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Skeletal radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sammon, Jennifer</au><au>Jain, Abhishek</au><au>Bleakney, Robert</au><au>Mohankumar, Rakesh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetic resonance imaging appearance of soft-tissue metastases: our experience at an orthopedic oncology center</atitle><jtitle>Skeletal radiology</jtitle><stitle>Skeletal Radiol</stitle><addtitle>Skeletal Radiol</addtitle><date>2017-04-01</date><risdate>2017</risdate><volume>46</volume><issue>4</issue><spage>513</spage><epage>521</epage><pages>513-521</pages><issn>0364-2348</issn><eissn>1432-2161</eissn><abstract>Objective
To assess the prevalence and magnetic resonance imaging appearance of metastasis presenting as a soft-tissue mass.
Materials and methods
A retrospective chart review was performed on 51 patients who presented to an orthopedic oncology center with soft-tissue masses, with a histology-proven diagnosis of soft-tissue metastasis, over a 14-year period. Their magnetic resonance imaging, primary origin, and follow-up have been assessed.
Results
Soft-tissue metastasis was identified in patients ranging from 18 to 85 years old. Most (80%) of the masses were located deep to the deep fascia. In our cohort of patients, melanoma was the most common primary malignancy contributing to soft-tissue metastasis (21.8%). Among soft-tissue metastasis from solid organs, breast and lung were the most frequent (9.1% each). Five patients had soft-tissue metastases from an unknown primary.
Conclusion
Imaging diagnosis of soft-tissue metastases is challenging as it can demonstrate imaging appearances similar to primary soft-tissue sarcoma. The presence of a known malignancy may not be evident in everyone, and even if available, histopathology will be necessary for diagnosis if this is the only site of recurrence/metastasis to differentiate from a primary soft-tissue sarcoma. Moreover, soft-tissue metastasis may be the initial presentation of a malignancy. Primary malignancies with soft-tissue metastasis carry a poor prognosis; hence, prompt diagnosis and management in essential.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>28180954</pmid><doi>10.1007/s00256-017-2582-0</doi><tpages>9</tpages></addata></record> |
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| ispartof | Skeletal radiology, 2017-04, Vol.46 (4), p.513-521 |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Adolescent Adult Aged Aged, 80 and over Female Humans Imaging Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medical imaging equipment Medicine Medicine & Public Health Melanoma Metastasis Middle Aged Nuclear Medicine Orthopedics Pathology Prevalence Radiology Retrospective Studies Sarcoma Scientific Article Soft Tissue Neoplasms - diagnostic imaging Soft Tissue Neoplasms - epidemiology Soft Tissue Neoplasms - secondary Young Adult |
| title | Magnetic resonance imaging appearance of soft-tissue metastases: our experience at an orthopedic oncology center |
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