Bloodless reperfusion with the oxygen carrier HBOC-201 in acute myocardial infarction: a novel platform for cardioprotective probes delivery

Reperfusion, despite being required for myocardial salvage, is associated with additional injury. We hypothesize that infarct size (IS) will be reduced by a period of bloodless reperfusion with hemoglobin-based oxygen carriers (HBOC) before blood-flow restoration. In the pig model, we first characte...

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Veröffentlicht in:	Basic research in cardiology 2017-03, Vol.112 (2), p.17-17, Article 17
Hauptverfasser:	García-Ruiz, Jose M., Galán-Arriola, Carlos, Fernández-Jiménez, Rodrigo, Aguero, Jaume, Sánchez-González, Javier, García-Alvarez, Ana, Nuno-Ayala, Mario, Dubé, Gregory P., Zafirelis, Zafiris, López-Martín, Gonzalo J., Bernal, Juan A., Lara-Pezzi, Enrique, Fuster, Valentín, Ibáñez, Borja
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiology Disease Models, Animal Heart - drug effects Hemodynamics - drug effects Hemoglobins - pharmacology Medicine Medicine & Public Health Myocardial Infarction - complications Myocardial Reperfusion - methods Myocardial Reperfusion Injury - prevention & control Original Contribution Random Allocation Swine
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