Normal and Altered Cytoarchitecture of the Inner Ear
Scanning electron microscope gave new insights into real morphology of the inner ear and has enhanced basic research. In fact, during the last twenty years, the cellular system that composes the organ of Corti and the vestibular apparatus has been clearly described by many authors. We now have a bet...
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| Veröffentlicht in: | Annals of the New York Academy of Sciences 1999-11, Vol.884 (1), p.69-84 |
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| container_end_page | 84 |
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| container_title | Annals of the New York Academy of Sciences |
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| creator | SERRA, A. GRASSO, D. L. COCUZZA, S. TROMBETTA, L. LA MANTIA, I. |
| description | Scanning electron microscope gave new insights into real morphology of the inner ear and has enhanced basic research. In fact, during the last twenty years, the cellular system that composes the organ of Corti and the vestibular apparatus has been clearly described by many authors. We now have a better understanding of each cell type and that they have a physiological functioning as ear and vestibular system.
In addition, new insights into the damage caused by many drugs, such as aminoglucosides, can be investigated by studying the morphological changes and the reparative process following the injury. Animals such as guinea pigs can be used as ideal models to investigate the alterations in the sensory epithelium of the cochlear and veastibular receptors following ototoxic poisoning. |
| doi_str_mv | 10.1111/j.1749-6632.1999.tb08637.x |
| format | Article |
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In addition, new insights into the damage caused by many drugs, such as aminoglucosides, can be investigated by studying the morphological changes and the reparative process following the injury. Animals such as guinea pigs can be used as ideal models to investigate the alterations in the sensory epithelium of the cochlear and veastibular receptors following ototoxic poisoning.</description><identifier>ISSN: 0077-8923</identifier><identifier>EISSN: 1749-6632</identifier><identifier>DOI: 10.1111/j.1749-6632.1999.tb08637.x</identifier><identifier>PMID: 10842585</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Aminoglycosides ; Animals ; Anti-Bacterial Agents - adverse effects ; Cochlea - drug effects ; Cochlea - pathology ; Cochlea - ultrastructure ; Ear, Inner - drug effects ; Ear, Inner - pathology ; Ear, Inner - ultrastructure ; Female ; Guinea Pigs ; Male ; Microscopy, Electron ; Organ of Corti - drug effects ; Organ of Corti - pathology ; Organ of Corti - ultrastructure</subject><ispartof>Annals of the New York Academy of Sciences, 1999-11, Vol.884 (1), p.69-84</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4419-fdbaca76cb2bd5c23828997ddaebe281dd15c7de90b23b97fd20dd662cbcdcae3</citedby><cites>FETCH-LOGICAL-c4419-fdbaca76cb2bd5c23828997ddaebe281dd15c7de90b23b97fd20dd662cbcdcae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1749-6632.1999.tb08637.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1749-6632.1999.tb08637.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10842585$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SERRA, A.</creatorcontrib><creatorcontrib>GRASSO, D. L.</creatorcontrib><creatorcontrib>COCUZZA, S.</creatorcontrib><creatorcontrib>TROMBETTA, L.</creatorcontrib><creatorcontrib>LA MANTIA, I.</creatorcontrib><title>Normal and Altered Cytoarchitecture of the Inner Ear</title><title>Annals of the New York Academy of Sciences</title><addtitle>Ann N Y Acad Sci</addtitle><description>Scanning electron microscope gave new insights into real morphology of the inner ear and has enhanced basic research. In fact, during the last twenty years, the cellular system that composes the organ of Corti and the vestibular apparatus has been clearly described by many authors. We now have a better understanding of each cell type and that they have a physiological functioning as ear and vestibular system.
In addition, new insights into the damage caused by many drugs, such as aminoglucosides, can be investigated by studying the morphological changes and the reparative process following the injury. Animals such as guinea pigs can be used as ideal models to investigate the alterations in the sensory epithelium of the cochlear and veastibular receptors following ototoxic poisoning.</description><subject>Aminoglycosides</subject><subject>Animals</subject><subject>Anti-Bacterial Agents - adverse effects</subject><subject>Cochlea - drug effects</subject><subject>Cochlea - pathology</subject><subject>Cochlea - ultrastructure</subject><subject>Ear, Inner - drug effects</subject><subject>Ear, Inner - pathology</subject><subject>Ear, Inner - ultrastructure</subject><subject>Female</subject><subject>Guinea Pigs</subject><subject>Male</subject><subject>Microscopy, Electron</subject><subject>Organ of Corti - drug effects</subject><subject>Organ of Corti - pathology</subject><subject>Organ of Corti - ultrastructure</subject><issn>0077-8923</issn><issn>1749-6632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkE1Lw0AQhhdRbP34CxI8eUnc3ST74UGopdZCqQcV9bTsx4Smpo3uptj-extSxKtzmcM8887wIHRJcEJ2db1ICM9kzFhKEyKlTBqDBUt5sjlA_d_RIepjzHksJE176CSEBcaEiowfox7BIqO5yPsom9V-qatIr1w0qBrw4KLhtqm1t_OyAdusPUR1ETVziCarFfhopP0ZOip0FeB830_Ry_3oefgQTx_Hk-FgGtssIzIunNFWc2YNNS63NBVUSMmd02CACuIcyS13ILGhqZG8cBQ7xxi1xjqrIT1FV13up6-_1hAatSyDharSK6jXQRHBuSBcCrlDbzrU-joED4X69OVS-60iWLXW1EK1alSrRrXW1N6a2uyWL_Z31mYJ7s9qp2kH3HbAd1nB9h_RavY-eGLte3EXUIYGNr8B2n8oxlOeq9fZWN29vj1l7HmqSPoDE_yMyA</recordid><startdate>199911</startdate><enddate>199911</enddate><creator>SERRA, A.</creator><creator>GRASSO, D. 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L.</au><au>COCUZZA, S.</au><au>TROMBETTA, L.</au><au>LA MANTIA, I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Normal and Altered Cytoarchitecture of the Inner Ear</atitle><jtitle>Annals of the New York Academy of Sciences</jtitle><addtitle>Ann N Y Acad Sci</addtitle><date>1999-11</date><risdate>1999</risdate><volume>884</volume><issue>1</issue><spage>69</spage><epage>84</epage><pages>69-84</pages><issn>0077-8923</issn><eissn>1749-6632</eissn><abstract>Scanning electron microscope gave new insights into real morphology of the inner ear and has enhanced basic research. In fact, during the last twenty years, the cellular system that composes the organ of Corti and the vestibular apparatus has been clearly described by many authors. We now have a better understanding of each cell type and that they have a physiological functioning as ear and vestibular system.
In addition, new insights into the damage caused by many drugs, such as aminoglucosides, can be investigated by studying the morphological changes and the reparative process following the injury. Animals such as guinea pigs can be used as ideal models to investigate the alterations in the sensory epithelium of the cochlear and veastibular receptors following ototoxic poisoning.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>10842585</pmid><doi>10.1111/j.1749-6632.1999.tb08637.x</doi><tpages>16</tpages></addata></record> |
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| ispartof | Annals of the New York Academy of Sciences, 1999-11, Vol.884 (1), p.69-84 |
| issn | 0077-8923 1749-6632 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aminoglycosides Animals Anti-Bacterial Agents - adverse effects Cochlea - drug effects Cochlea - pathology Cochlea - ultrastructure Ear, Inner - drug effects Ear, Inner - pathology Ear, Inner - ultrastructure Female Guinea Pigs Male Microscopy, Electron Organ of Corti - drug effects Organ of Corti - pathology Organ of Corti - ultrastructure |
| title | Normal and Altered Cytoarchitecture of the Inner Ear |
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