Mechanisms and Mediators of the Skeletal Muscle Repeated Bout Effect

Skeletal muscle adapts to exercise-induced damage by orchestrating several but still poorly understood mechanisms that endow protection from subsequent damage. Known widely as the repeated bout effect, we propose that neural adaptations, alterations to muscle mechanical properties, structural remode...

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Veröffentlicht in:Exercise and sport sciences reviews 2017-01, Vol.45 (1), p.24-33
Hauptverfasser: Hyldahl, Robert D, Chen, Trevor C, Nosaka, Kazunori
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creator Hyldahl, Robert D
Chen, Trevor C
Nosaka, Kazunori
description Skeletal muscle adapts to exercise-induced damage by orchestrating several but still poorly understood mechanisms that endow protection from subsequent damage. Known widely as the repeated bout effect, we propose that neural adaptations, alterations to muscle mechanical properties, structural remodeling of the extracellular matrix, and biochemical signaling work in concert to coordinate the protective adaptation.
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source MEDLINE; Journals@Ovid LWW Legacy Archive; EZB-FREE-00999 freely available EZB journals
subjects Adaptation, Physiological
Biomechanical Phenomena
Exercise - physiology
Extracellular Matrix - physiology
Humans
Inflammation - physiopathology
Motor Neurons - physiology
Muscle, Skeletal - injuries
Muscle, Skeletal - innervation
Muscle, Skeletal - physiology
Tendons - physiology
title Mechanisms and Mediators of the Skeletal Muscle Repeated Bout Effect
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