Bioavailability and Kidney Responses to Diclofenac in the Fathead Minnow (Pimephales promelas)

Diclofenac is one of the most widely prescribed nonsteroidal anti-inflammatory drugs worldwide. It is frequently detected in surface waters; however, whether this pharmaceutical poses a risk to aquatic organisms is debated. Here we quantified the uptake of diclofenac by the fathead minnow (Pimephale...

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Veröffentlicht in:	Environmental science & technology 2017-02, Vol.51 (3), p.1764-1774
Hauptverfasser:	Bickley, Lisa K, van Aerle, Ronny, Brown, A. Ross, Hargreaves, Adam, Huby, Russell, Cammack, Victoria, Jackson, Richard, Santos, Eduarda M, Tyler, Charles R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aquatic life Bioaccumulation Biological Availability Cyprinidae - metabolism Diclofenac - metabolism Fish Kidney - metabolism Kidneys Nonsteroidal anti-inflammatory drugs Pimephales promelas Risk factors Water Pollutants, Chemical - metabolism
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