In Vitro and In Vivo Study of Solid Lipid Nanoparticles Loaded with Superparamagnetic Iron Oxide

Solid Lipid Nanoparticles (SLN) are already under investigation as a pharmaceutical tool able to change the pharmacokinetic and biodistribution of carried molecules. SLN are able to target drugs to lymph after duodenal administration and to overcome the Blood Brain Barrier (BBB). In this study, supe...

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Veröffentlicht in:	Journal of drug targeting 2003-01, Vol.11 (1), p.19-24
Hauptverfasser:	Peira, Elena, Marzola, Pasquina, Podio, Valerio, Aime, Silvio, Sbarbati, Andrea, Gasco, Maria Rosa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood-Brain Barrier - drug effects Blood-Brain Barrier - physiology Brain - drug effects Brain - metabolism Brain targeting Chemistry, Pharmaceutical Contrast media. Radiopharmaceuticals Ferrosoferric Oxide General pharmacology Iron - administration & dosage Iron - pharmacokinetics Lipids - administration & dosage Lipids - pharmacokinetics Magnetic resonance imaging Magnetic Resonance Imaging - methods Medical sciences Nanotechnology - methods Oxides - administration & dosage Oxides - pharmacokinetics Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Rats Rats, Sprague-Dawley Solid lipid nanoparticles Superparamagnetic iron oxide nanoparticles
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