In vitro hemolytic activity of Lonomia obliqua caterpillar bristle extract on human and Wistar rat erythrocytes

Human accidental envenomation caused by skin contact with the bristles of Lonomia obliqua caterpillar causes coagulation and fibrinolysis disorders. Alterations of hematologic parameters are observed only in severe cases of envenomation, but with no clinical evidence of intravascular hemolysis. Howe...

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Veröffentlicht in:	Toxicon (Oxford) 2003-06, Vol.41 (7), p.831-839
Hauptverfasser:	Seibert, Carla Simone, Shinohara, Elvira Maria Guerra, Sano-Martins, Ida Sigueko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal poisons toxicology. Antivenoms Animals Arthropod Venoms - administration & dosage Arthropod Venoms - toxicity Biological and medical sciences Dose-Response Relationship, Drug Electrophoresis, Polyacrylamide Gel Erythrocyte membrane proteins Erythrocytes - drug effects Hemolysis Hemolysis - drug effects Hemorrhage - chemically induced Humans Lepidoptera Lonomia obliqua Male Medical sciences Phospholipases A - administration & dosage Phospholipases A - toxicity Proteolysis Rats Rats, Wistar Toxicology
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