A Patient with Postoperative Mercury Contamination of the Peritoneum
Case Report: Peritoneal exposure to mercury has been rarely reported and long-term consequences of this type of exposure have not been documented. We report the clinical course of a patient who has survived almost eight years with a massive intraperitoneal load of mercury. She has suffered formicati...
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Veröffentlicht in: | Journal of toxicology. Clinical toxicology 2003-01, Vol.41 (2), p.175-180 |
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creator | Haas, Nelson S. Shih, Richard Gochfeld, Michael |
description | Case Report: Peritoneal exposure to mercury has been rarely reported and long-term consequences of this type of exposure have not been documented. We report the clinical course of a patient who has survived almost eight years with a massive intraperitoneal load of mercury. She has suffered formication, pruritis, fatigue, irritiability, insomnia, alopecia, dizziness, a gait disturbance, loss of balance and multiple falls, abdominal pain, choking, and headaches. Two courses of chelation with dimercaptosuccinic acid using the standard protocol were undertaken, resulting in increased daily excretion, but without demonstrable objective or subjective benefit or lasting effect. She had multiple medical problems before the mercury intoxication, which complicates the attribution of all her problems to mercury intoxication. It is of particular interest that the patient survived and did not suffer any marked cognitive deterioration. She died in 2002 shortly after being diagnosed with lung cancer and declaring that she would fight it. Phasing out of mercury-weighted tubes is recommended. |
doi_str_mv | 10.1081/CLT-120019134 |
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We report the clinical course of a patient who has survived almost eight years with a massive intraperitoneal load of mercury. She has suffered formication, pruritis, fatigue, irritiability, insomnia, alopecia, dizziness, a gait disturbance, loss of balance and multiple falls, abdominal pain, choking, and headaches. Two courses of chelation with dimercaptosuccinic acid using the standard protocol were undertaken, resulting in increased daily excretion, but without demonstrable objective or subjective benefit or lasting effect. She had multiple medical problems before the mercury intoxication, which complicates the attribution of all her problems to mercury intoxication. It is of particular interest that the patient survived and did not suffer any marked cognitive deterioration. She died in 2002 shortly after being diagnosed with lung cancer and declaring that she would fight it. Phasing out of mercury-weighted tubes is recommended.</description><identifier>ISSN: 0731-3810</identifier><identifier>EISSN: 1097-9875</identifier><identifier>DOI: 10.1081/CLT-120019134</identifier><identifier>PMID: 12733856</identifier><language>eng</language><publisher>United States: Informa UK Ltd</publisher><subject>Chelating Agents - therapeutic use ; Creatine - blood ; Crohn Disease - complications ; Electroencephalography ; Fatal Outcome ; Female ; Humans ; Intestinal Obstruction - complications ; Intestinal Obstruction - diagnostic imaging ; Intestinal Obstruction - therapy ; Intubation, Gastrointestinal ; Irritable Mood ; Mercury - metabolism ; Mercury Poisoning - diagnostic imaging ; Mercury Poisoning - etiology ; Mercury Poisoning - therapy ; Middle Aged ; Neurotoxicity Syndromes - etiology ; Neurotoxicity Syndromes - therapy ; Peritoneum - physiology ; Postoperative Complications - diagnostic imaging ; Postoperative Complications - etiology ; Postoperative Complications - therapy ; Radiography ; Succimer - therapeutic use</subject><ispartof>Journal of toxicology. Clinical toxicology, 2003-01, Vol.41 (2), p.175-180</ispartof><rights>2003 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2003</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-e107196d722e9f4b40d353fbd0b7df099cb3dae6908d92df10bca5a27358444c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1081/CLT-120019134$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1081/CLT-120019134$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12733856$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Haas, Nelson S.</creatorcontrib><creatorcontrib>Shih, Richard</creatorcontrib><creatorcontrib>Gochfeld, Michael</creatorcontrib><title>A Patient with Postoperative Mercury Contamination of the Peritoneum</title><title>Journal of toxicology. Clinical toxicology</title><addtitle>J Toxicol Clin Toxicol</addtitle><description>Case Report: Peritoneal exposure to mercury has been rarely reported and long-term consequences of this type of exposure have not been documented. We report the clinical course of a patient who has survived almost eight years with a massive intraperitoneal load of mercury. She has suffered formication, pruritis, fatigue, irritiability, insomnia, alopecia, dizziness, a gait disturbance, loss of balance and multiple falls, abdominal pain, choking, and headaches. Two courses of chelation with dimercaptosuccinic acid using the standard protocol were undertaken, resulting in increased daily excretion, but without demonstrable objective or subjective benefit or lasting effect. She had multiple medical problems before the mercury intoxication, which complicates the attribution of all her problems to mercury intoxication. It is of particular interest that the patient survived and did not suffer any marked cognitive deterioration. She died in 2002 shortly after being diagnosed with lung cancer and declaring that she would fight it. Phasing out of mercury-weighted tubes is recommended.</description><subject>Chelating Agents - therapeutic use</subject><subject>Creatine - blood</subject><subject>Crohn Disease - complications</subject><subject>Electroencephalography</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Humans</subject><subject>Intestinal Obstruction - complications</subject><subject>Intestinal Obstruction - diagnostic imaging</subject><subject>Intestinal Obstruction - therapy</subject><subject>Intubation, Gastrointestinal</subject><subject>Irritable Mood</subject><subject>Mercury - metabolism</subject><subject>Mercury Poisoning - diagnostic imaging</subject><subject>Mercury Poisoning - etiology</subject><subject>Mercury Poisoning - therapy</subject><subject>Middle Aged</subject><subject>Neurotoxicity Syndromes - etiology</subject><subject>Neurotoxicity Syndromes - therapy</subject><subject>Peritoneum - physiology</subject><subject>Postoperative Complications - diagnostic imaging</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - therapy</subject><subject>Radiography</subject><subject>Succimer - therapeutic use</subject><issn>0731-3810</issn><issn>1097-9875</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD1PwzAURS0EoqUwsiJPbIHn2InjsQqfUhEdymw5yYuSKrGL44D67wlqYXrS1dHVu4eQawZ3DDJ2n682EYsBmGJcnJA5AyUjlcnklMxBchbxjMGMXAzDFgA4T9JzMmOx5DxL0jl5WNK1CS3aQL_b0NC1G4LboZ-yL6Rv6MvR72nubDB9a6fUWepqGhqka_RtcBbH_pKc1aYb8Op4F-Tj6XGTv0Sr9-fXfLmKSi5FiJCBZCqtZByjqkUhoOIJr4sKClnVoFRZ8MpgqiCrVFzVDIrSJGb6NcmEECVfkNtD7867zxGHoPt2KLHrjEU3DpplMk2UEhN4cwTHosdK73zbG7_Xf7snQB6A1tbO96ZB04WmNB711o3eTis0A_1rWE-G9b9h_gNLKGvl</recordid><startdate>20030101</startdate><enddate>20030101</enddate><creator>Haas, Nelson S.</creator><creator>Shih, Richard</creator><creator>Gochfeld, Michael</creator><general>Informa UK Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T2</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20030101</creationdate><title>A Patient with Postoperative Mercury Contamination of the Peritoneum</title><author>Haas, Nelson S. ; Shih, Richard ; Gochfeld, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-e107196d722e9f4b40d353fbd0b7df099cb3dae6908d92df10bca5a27358444c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Chelating Agents - therapeutic use</topic><topic>Creatine - blood</topic><topic>Crohn Disease - complications</topic><topic>Electroencephalography</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Humans</topic><topic>Intestinal Obstruction - complications</topic><topic>Intestinal Obstruction - diagnostic imaging</topic><topic>Intestinal Obstruction - therapy</topic><topic>Intubation, Gastrointestinal</topic><topic>Irritable Mood</topic><topic>Mercury - metabolism</topic><topic>Mercury Poisoning - diagnostic imaging</topic><topic>Mercury Poisoning - etiology</topic><topic>Mercury Poisoning - therapy</topic><topic>Middle Aged</topic><topic>Neurotoxicity Syndromes - etiology</topic><topic>Neurotoxicity Syndromes - therapy</topic><topic>Peritoneum - physiology</topic><topic>Postoperative Complications - diagnostic imaging</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - therapy</topic><topic>Radiography</topic><topic>Succimer - therapeutic use</topic><toplevel>online_resources</toplevel><creatorcontrib>Haas, Nelson S.</creatorcontrib><creatorcontrib>Shih, Richard</creatorcontrib><creatorcontrib>Gochfeld, Michael</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of toxicology. Clinical toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Haas, Nelson S.</au><au>Shih, Richard</au><au>Gochfeld, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Patient with Postoperative Mercury Contamination of the Peritoneum</atitle><jtitle>Journal of toxicology. Clinical toxicology</jtitle><addtitle>J Toxicol Clin Toxicol</addtitle><date>2003-01-01</date><risdate>2003</risdate><volume>41</volume><issue>2</issue><spage>175</spage><epage>180</epage><pages>175-180</pages><issn>0731-3810</issn><eissn>1097-9875</eissn><abstract>Case Report: Peritoneal exposure to mercury has been rarely reported and long-term consequences of this type of exposure have not been documented. We report the clinical course of a patient who has survived almost eight years with a massive intraperitoneal load of mercury. She has suffered formication, pruritis, fatigue, irritiability, insomnia, alopecia, dizziness, a gait disturbance, loss of balance and multiple falls, abdominal pain, choking, and headaches. Two courses of chelation with dimercaptosuccinic acid using the standard protocol were undertaken, resulting in increased daily excretion, but without demonstrable objective or subjective benefit or lasting effect. She had multiple medical problems before the mercury intoxication, which complicates the attribution of all her problems to mercury intoxication. It is of particular interest that the patient survived and did not suffer any marked cognitive deterioration. She died in 2002 shortly after being diagnosed with lung cancer and declaring that she would fight it. Phasing out of mercury-weighted tubes is recommended.</abstract><cop>United States</cop><pub>Informa UK Ltd</pub><pmid>12733856</pmid><doi>10.1081/CLT-120019134</doi><tpages>6</tpages></addata></record> |
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source | Taylor & Francis:Master (3349 titles); MEDLINE; Taylor & Francis Medical Library - CRKN |
subjects | Chelating Agents - therapeutic use Creatine - blood Crohn Disease - complications Electroencephalography Fatal Outcome Female Humans Intestinal Obstruction - complications Intestinal Obstruction - diagnostic imaging Intestinal Obstruction - therapy Intubation, Gastrointestinal Irritable Mood Mercury - metabolism Mercury Poisoning - diagnostic imaging Mercury Poisoning - etiology Mercury Poisoning - therapy Middle Aged Neurotoxicity Syndromes - etiology Neurotoxicity Syndromes - therapy Peritoneum - physiology Postoperative Complications - diagnostic imaging Postoperative Complications - etiology Postoperative Complications - therapy Radiography Succimer - therapeutic use |
title | A Patient with Postoperative Mercury Contamination of the Peritoneum |
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