Development of an Automaton Model of Rotational Activity Driving Atrial Fibrillation

Abstract Background Atrial fibrillation (AF) is difficult to treat effectively, owing to uncertainty in where to best ablate to eliminate arrhythmogenic substrate. A model providing insight into the electrical activation events would be useful to guide catheter ablation strategy. Method A two-dimens...

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Veröffentlicht in:	Computers in biology and medicine 2017-04, Vol.83, p.166-181
Hauptverfasser:	Ciaccio, E.J, Biviano, A.B, Wan, E.Y, Peters, N.S, Garan, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Action Potentials Anisotropy Atrial fibrillation Atrial Fibrillation - physiopathology Barriers Biological Clocks Boundaries Cardiac arrhythmia Cardiovascular disease Clusters Collagen Computer Simulation Conduction block Electric pulses Fibrillation Fibrosis Heart Heart Atria - physiopathology Heart Conduction System - physiopathology Humans Internal Medicine Lesions Medical instruments Models, Cardiovascular Other Refractory period Rotation Rotational activity Rotor Rotors Simulation Thermal resistance Vortex Vortices Wave fronts
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