Phosphorylase kinase β affects colorectal cancer cell growth and represents a novel prognostic biomarker

Purpose To study the expression and intracellular localization of phosphorylase kinase β (PHKβ) protein in colorectal cancers (CRCs), analyze its correlation with clinicopathological features and prognosis, and study the biological roles and mechanism-of-action of PHKβ in CRC cell lines. Methods Qua...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2017-06, Vol.143 (6), p.971-980
Hauptverfasser:	Wang, Guanghui, Shen, Wenbin, Liu, Chen-ying, Liu, Yun, Wu, Tingyu, Cui, Ximao, Yu, Tong, Zhu, Yilian, Song, Jinglue, Du, Peng, Cui, Long
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Animals Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Cancer Research Cell Proliferation - genetics Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Female Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic HCT116 Cells Hematology Humans Internal Medicine Male Medicine Medicine & Public Health Mice Mice, Nude Middle Aged Oncology Original Article – Cancer Research Phosphorylase Kinase - genetics Phosphorylase Kinase - physiology Prognosis Tumor Cells, Cultured
Online-Zugang:	Volltext
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