Re-expression of Detachment-inducible Chloride Channel mCLCA5 Suppresses Growth of Metastatic Breast Cancer Cells

The calcium-activated chloride channel hCLCA2 has been identified as a candidate tumor suppressor in human breast cancer. It is greatly down-regulated in breast cancer, and its re-expression suppresses tumorigenesis by an unknown mechanism. To establish a mouse model, we identified the mouse ortholo...

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Veröffentlicht in:	The Journal of biological chemistry 2004-10, Vol.279 (40), p.41634-41641
Hauptverfasser:	Beckley, Janel R, Pauli, Bendicht U, Elble, Randolph C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Breast Neoplasms - pathology Cell Division Cell Line Cell Line, Tumor Chloride Channels - physiology Epithelial Cells - cytology Female Gene Expression Regulation, Neoplastic Mammary Glands, Animal - cytology Mice Molecular Sequence Data Neoplasm Metastasis - pathology Sequence Alignment Tissue Distribution Tumor Suppressor Proteins - physiology
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