In-vitro culture of individual mouse preimplantation embryos: the role of embryo density, microwells, oxygen, timing and conditioned media

Highlights • Individual culture of preimplantation mouse embryos is detrimental during both the precompaction and postcompaction stages, demonstrated by reduced hatching rate and blastocyst cell numbers. • The effect of embryo density on singly cultured embryos is dependent on the incubator oxygen c...

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