17- [ 16,17-Dihydroxycyclooctatinyl]-hexaketide ester from Streptomyces sp. SR107

A new hexaketide acid esterified by the 17-hydroxyl group of 16,17-dihydroxycyclooctatin, namely 17-[16,17-dihydroxycyclooctatinyl]-hexaketide ester（1）, a member of the group of rare bacterial diterpenes with a fused 5-8-5 ring system was isolated from strain Streptomyces sp. SR107. The structure wa...

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Veröffentlicht in:	Chinese journal of natural medicines 2016-12, Vol.14 (12), p.931-933
Hauptverfasser:	LIU, Meng-Yu-Jie, LI, Shan-Ren, Chun-Hua, LU
Format:	Artikel
Sprache:	eng
Schlagworte:	17-[16,17-Dihydroxycyclooctatinyl]-hexaketide ester Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity Bacteria - drug effects Diterpenes Diterpenes - chemistry Diterpenes - metabolism Diterpenes - pharmacology Esters - chemistry Esters - pharmacology Magnetic Resonance Spectroscopy Molecular Structure Streptomyces - chemistry Streptomyces sp. SR107
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description	A new hexaketide acid esterified by the 17-hydroxyl group of 16,17-dihydroxycyclooctatin, namely 17-[16,17-dihydroxycyclooctatinyl]-hexaketide ester（1）, a member of the group of rare bacterial diterpenes with a fused 5-8-5 ring system was isolated from strain Streptomyces sp. SR107. The structure was determined on the basis of its spectral data（~1H NMR, ~（13） C NMR, ~1H-~1H COSY, HSQC, HMBC, NOESY, IR and HR-ESI-MS）. The antibacterial activity was also evaluated in this paper.
doi_str_mv	10.1016/S1875-5364(17)30018-3
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SR107</title><title>Chinese journal of natural medicines</title><addtitle>Chinese JOurnal of Natural Medicines</addtitle><description>A new hexaketide acid esterified by the 17-hydroxyl group of 16,17-dihydroxycyclooctatin, namely 17-[16,17-dihydroxycyclooctatinyl]-hexaketide ester（1）, a member of the group of rare bacterial diterpenes with a fused 5-8-5 ring system was isolated from strain Streptomyces sp. SR107. The structure was determined on the basis of its spectral data（~1H NMR, ~（13） C NMR, ~1H-~1H COSY, HSQC, HMBC, NOESY, IR and HR-ESI-MS）. 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subjects	17-[16,17-Dihydroxycyclooctatinyl]-hexaketide ester Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity Bacteria - drug effects Diterpenes Diterpenes - chemistry Diterpenes - metabolism Diterpenes - pharmacology Esters - chemistry Esters - pharmacology Magnetic Resonance Spectroscopy Molecular Structure Streptomyces - chemistry Streptomyces sp. SR107
title	17- [ 16,17-Dihydroxycyclooctatinyl]-hexaketide ester from Streptomyces sp. SR107
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