Effects of xylazine and dexmedetomidine on equine articular chondrocytes in vitro

To assess the effects of xylazine and dexmedetomidine on equine chondrocytes, in vitro. Prospective, experimental study. Equine articular chondrocytes from five male horses. Chondrocytes were isolated from healthy equine articular cartilage of the metacarpo/metatarsophalangeal joints. Cell viability...

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Veröffentlicht in:	Veterinary anaesthesia and analgesia 2017-03, Vol.44 (2), p.295-308
Hauptverfasser:	Mancini, Francesco, Nannarone, Sara, Buratta, Sandra, Ferrara, Giuseppina, Stabile, Anna Maria, Vuerich, Matteo, Santinelli, Isabella, Pistilli, Alessandra, Chiaradia, Elisabetta
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-2 Receptor Agonists - administration & dosage Adrenergic alpha-2 Receptor Agonists - pharmacology Animals apoptosis Cartilage, Articular - cytology Cell Membrane - drug effects Cell Survival - drug effects Chondrocytes - drug effects chondrotoxicity dexmedetomidine Dexmedetomidine - pharmacology Horses In Vitro Techniques - veterinary Male Prospective Studies Tetrazolium Salts - pharmacology xylazine Xylazine - pharmacology α2-agonists
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