USG-guided injection of corticosteroid for lateral epicondylitis does not improve clinical outcomes: a prospective randomised study
Background Corticosteroid injection used to be the treatment of choice for lateral epicondylitis. Most injections are performed blindly. In the blinded technique, it could be difficult to determine the exact pathological localisation. The purpose of this single-blinded, randomised controlled clinica...
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Veröffentlicht in: | Archives of orthopaedic and trauma surgery 2017-05, Vol.137 (5), p.601-606 |
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description | Background
Corticosteroid injection used to be the treatment of choice for lateral epicondylitis. Most injections are performed blindly. In the blinded technique, it could be difficult to determine the exact pathological localisation. The purpose of this single-blinded, randomised controlled clinical study was to compare the clinical therapeutic effects of blinded and USG-guided corticosteroid injection therapy in lateral epicondylitis.
Patients and methods
Forty patients with chronic lateral epicondylitis were included in this clinical trial. The patients were randomly allocated to blinded group or USG-guided injection group according to a computer-generated randomisation list. All blinded injections were administered by an orthopaedic surgeon and all ultrasound-guided injections were made by a radiologist experienced in this technique. All patients were injected under aseptic conditions using 40 mg/2 mL methylprednisolone acetate. The outcomes of both treatments were assessed by an independent assessor at pre-injection, then at 6-week and 3- and 6-month follow-up assessments. The assessor evaluated the q-DASH, VAS, and grip strength scores.
Results
No statistically significant difference was determined between the groups in respect of the Q-DASH and grip strength scores preoperatively and at 6 weeks and 3 and 6 months post-injection. No statistically significant difference was determined between the groups in respect of the VAS scores preoperatively and at 6 weeks and 6 months. No systemic or local complications were reported during the treatment.
Conclusion
There was no statistically significant difference compared to the blinded injection technique, and the mean score differences between the groups are of no clinical relevance. |
doi_str_mv | 10.1007/s00402-017-2657-3 |
format | Article |
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Corticosteroid injection used to be the treatment of choice for lateral epicondylitis. Most injections are performed blindly. In the blinded technique, it could be difficult to determine the exact pathological localisation. The purpose of this single-blinded, randomised controlled clinical study was to compare the clinical therapeutic effects of blinded and USG-guided corticosteroid injection therapy in lateral epicondylitis.
Patients and methods
Forty patients with chronic lateral epicondylitis were included in this clinical trial. The patients were randomly allocated to blinded group or USG-guided injection group according to a computer-generated randomisation list. All blinded injections were administered by an orthopaedic surgeon and all ultrasound-guided injections were made by a radiologist experienced in this technique. All patients were injected under aseptic conditions using 40 mg/2 mL methylprednisolone acetate. The outcomes of both treatments were assessed by an independent assessor at pre-injection, then at 6-week and 3- and 6-month follow-up assessments. The assessor evaluated the q-DASH, VAS, and grip strength scores.
Results
No statistically significant difference was determined between the groups in respect of the Q-DASH and grip strength scores preoperatively and at 6 weeks and 3 and 6 months post-injection. No statistically significant difference was determined between the groups in respect of the VAS scores preoperatively and at 6 weeks and 6 months. No systemic or local complications were reported during the treatment.
Conclusion
There was no statistically significant difference compared to the blinded injection technique, and the mean score differences between the groups are of no clinical relevance.</description><identifier>ISSN: 0936-8051</identifier><identifier>EISSN: 1434-3916</identifier><identifier>DOI: 10.1007/s00402-017-2657-3</identifier><identifier>PMID: 28258434</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Elbow ; Elbow - diagnostic imaging ; Female ; Glucocorticoids - administration & dosage ; Humans ; Injections - methods ; Male ; Medicine ; Medicine & Public Health ; Methylprednisolone - administration & dosage ; Middle Aged ; Orthopaedic Surgery ; Orthopedics ; Tennis Elbow - drug therapy ; Treatment Outcome ; Ultrasonography - methods</subject><ispartof>Archives of orthopaedic and trauma surgery, 2017-05, Vol.137 (5), p.601-606</ispartof><rights>Springer-Verlag Berlin Heidelberg 2017</rights><rights>Archives of Orthopaedic and Trauma Surgery is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-349e491edf231c147c84872a6e4f5f3df93a10c41bad5a3cf673180b9a1e58693</citedby><cites>FETCH-LOGICAL-c372t-349e491edf231c147c84872a6e4f5f3df93a10c41bad5a3cf673180b9a1e58693</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00402-017-2657-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00402-017-2657-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28258434$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gulabi, Deniz</creatorcontrib><creatorcontrib>Uysal, Mehmet Ali</creatorcontrib><creatorcontrib>Akça, Ahmet</creatorcontrib><creatorcontrib>Colak, Ilker</creatorcontrib><creatorcontrib>Çeçen, Gultekin Sıtkı</creatorcontrib><creatorcontrib>Gumustas, Seyitali</creatorcontrib><title>USG-guided injection of corticosteroid for lateral epicondylitis does not improve clinical outcomes: a prospective randomised study</title><title>Archives of orthopaedic and trauma surgery</title><addtitle>Arch Orthop Trauma Surg</addtitle><addtitle>Arch Orthop Trauma Surg</addtitle><description>Background
Corticosteroid injection used to be the treatment of choice for lateral epicondylitis. Most injections are performed blindly. In the blinded technique, it could be difficult to determine the exact pathological localisation. The purpose of this single-blinded, randomised controlled clinical study was to compare the clinical therapeutic effects of blinded and USG-guided corticosteroid injection therapy in lateral epicondylitis.
Patients and methods
Forty patients with chronic lateral epicondylitis were included in this clinical trial. The patients were randomly allocated to blinded group or USG-guided injection group according to a computer-generated randomisation list. All blinded injections were administered by an orthopaedic surgeon and all ultrasound-guided injections were made by a radiologist experienced in this technique. All patients were injected under aseptic conditions using 40 mg/2 mL methylprednisolone acetate. The outcomes of both treatments were assessed by an independent assessor at pre-injection, then at 6-week and 3- and 6-month follow-up assessments. The assessor evaluated the q-DASH, VAS, and grip strength scores.
Results
No statistically significant difference was determined between the groups in respect of the Q-DASH and grip strength scores preoperatively and at 6 weeks and 3 and 6 months post-injection. No statistically significant difference was determined between the groups in respect of the VAS scores preoperatively and at 6 weeks and 6 months. No systemic or local complications were reported during the treatment.
Conclusion
There was no statistically significant difference compared to the blinded injection technique, and the mean score differences between the groups are of no clinical relevance.</description><subject>Adult</subject><subject>Elbow</subject><subject>Elbow - diagnostic imaging</subject><subject>Female</subject><subject>Glucocorticoids - administration & dosage</subject><subject>Humans</subject><subject>Injections - methods</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Methylprednisolone - administration & dosage</subject><subject>Middle Aged</subject><subject>Orthopaedic Surgery</subject><subject>Orthopedics</subject><subject>Tennis Elbow - drug therapy</subject><subject>Treatment Outcome</subject><subject>Ultrasonography - methods</subject><issn>0936-8051</issn><issn>1434-3916</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kU9rVDEUxYModqx-ADcScOMmNn_fS9xJ0SoUumi7DpnkpmR472VM8oRZ94ubYaqC4CqE87vnnstB6C2jHxml40WlVFJOKBsJH9RIxDO0YVJIIgwbnqMNNWIgmip2hl7VuqOUcW3oS3TGNVe6gxv0eH97RR7WFCDgtOzAt5QXnCP2ubTkc21Qcgo45oIn1z9uwrDvwhIOU2qp4pCh4iU3nOZ9yT8B-yktyXcur83nGeon7HCX6v7o3oHilpDnVPvK2tZweI1eRDdVePP0nqP7r1_uLr-R65ur75efr4kXI29ESAPSMAiRC-aZHL2WeuRuABlVFCEa4Rj1km1dUE74OIyCabo1joHSgxHn6MPJt4f5sUJttofwME1ugbxWy_QopVRCqI6-_wfd5bUsPZ3lfGBaG614p9iJ8v26WiDafUmzKwfLqD02ZE8N2d6QPTZkRZ959-S8bmcIfyZ-V9IBfgJql5YHKH9X_9_1F7x6nZY</recordid><startdate>20170501</startdate><enddate>20170501</enddate><creator>Gulabi, Deniz</creator><creator>Uysal, Mehmet Ali</creator><creator>Akça, Ahmet</creator><creator>Colak, Ilker</creator><creator>Çeçen, Gultekin Sıtkı</creator><creator>Gumustas, Seyitali</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20170501</creationdate><title>USG-guided injection of corticosteroid for lateral epicondylitis does not improve clinical outcomes: a prospective randomised study</title><author>Gulabi, Deniz ; Uysal, Mehmet Ali ; Akça, Ahmet ; Colak, Ilker ; Çeçen, Gultekin Sıtkı ; Gumustas, Seyitali</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-349e491edf231c147c84872a6e4f5f3df93a10c41bad5a3cf673180b9a1e58693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Elbow</topic><topic>Elbow - diagnostic imaging</topic><topic>Female</topic><topic>Glucocorticoids - administration & dosage</topic><topic>Humans</topic><topic>Injections - methods</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Methylprednisolone - administration & dosage</topic><topic>Middle Aged</topic><topic>Orthopaedic Surgery</topic><topic>Orthopedics</topic><topic>Tennis Elbow - drug therapy</topic><topic>Treatment Outcome</topic><topic>Ultrasonography - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gulabi, Deniz</creatorcontrib><creatorcontrib>Uysal, Mehmet Ali</creatorcontrib><creatorcontrib>Akça, Ahmet</creatorcontrib><creatorcontrib>Colak, Ilker</creatorcontrib><creatorcontrib>Çeçen, Gultekin Sıtkı</creatorcontrib><creatorcontrib>Gumustas, Seyitali</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of orthopaedic and trauma surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gulabi, Deniz</au><au>Uysal, Mehmet Ali</au><au>Akça, Ahmet</au><au>Colak, Ilker</au><au>Çeçen, Gultekin Sıtkı</au><au>Gumustas, Seyitali</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>USG-guided injection of corticosteroid for lateral epicondylitis does not improve clinical outcomes: a prospective randomised study</atitle><jtitle>Archives of orthopaedic and trauma surgery</jtitle><stitle>Arch Orthop Trauma Surg</stitle><addtitle>Arch Orthop Trauma Surg</addtitle><date>2017-05-01</date><risdate>2017</risdate><volume>137</volume><issue>5</issue><spage>601</spage><epage>606</epage><pages>601-606</pages><issn>0936-8051</issn><eissn>1434-3916</eissn><abstract>Background
Corticosteroid injection used to be the treatment of choice for lateral epicondylitis. Most injections are performed blindly. In the blinded technique, it could be difficult to determine the exact pathological localisation. The purpose of this single-blinded, randomised controlled clinical study was to compare the clinical therapeutic effects of blinded and USG-guided corticosteroid injection therapy in lateral epicondylitis.
Patients and methods
Forty patients with chronic lateral epicondylitis were included in this clinical trial. The patients were randomly allocated to blinded group or USG-guided injection group according to a computer-generated randomisation list. All blinded injections were administered by an orthopaedic surgeon and all ultrasound-guided injections were made by a radiologist experienced in this technique. All patients were injected under aseptic conditions using 40 mg/2 mL methylprednisolone acetate. The outcomes of both treatments were assessed by an independent assessor at pre-injection, then at 6-week and 3- and 6-month follow-up assessments. The assessor evaluated the q-DASH, VAS, and grip strength scores.
Results
No statistically significant difference was determined between the groups in respect of the Q-DASH and grip strength scores preoperatively and at 6 weeks and 3 and 6 months post-injection. No statistically significant difference was determined between the groups in respect of the VAS scores preoperatively and at 6 weeks and 6 months. No systemic or local complications were reported during the treatment.
Conclusion
There was no statistically significant difference compared to the blinded injection technique, and the mean score differences between the groups are of no clinical relevance.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>28258434</pmid><doi>10.1007/s00402-017-2657-3</doi><tpages>6</tpages></addata></record> |
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source | MEDLINE; SpringerLink Journals - AutoHoldings |
subjects | Adult Elbow Elbow - diagnostic imaging Female Glucocorticoids - administration & dosage Humans Injections - methods Male Medicine Medicine & Public Health Methylprednisolone - administration & dosage Middle Aged Orthopaedic Surgery Orthopedics Tennis Elbow - drug therapy Treatment Outcome Ultrasonography - methods |
title | USG-guided injection of corticosteroid for lateral epicondylitis does not improve clinical outcomes: a prospective randomised study |
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