RelB attenuates cigarette smoke extract-induced apoptosis in association with transcriptional regulation of the aryl hydrocarbon receptor

Chronic obstructive pulmonary disease (COPD) is a chronic and prevalent respiratory disease caused primarily by long term inhalation of cigarette smoke. A major hallmark of COPD is elevated apoptosis of structural lung cells including fibroblasts. The NF-κB member RelB may suppress apoptosis in resp...

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Veröffentlicht in:Free radical biology & medicine 2017-07, Vol.108, p.19-31
Hauptverfasser: Iu, Matthew, Zago, Michela, Rico de Souza, Angela, Bouttier, Manuella, Pareek, Swati, White, John H., Hamid, Qutayba, Eidelman, David H., Baglole, Carolyn J.
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Sprache:eng
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