Molecular analyses on Neospora caninum-triggered NETosis in the caprine system

Neospora caninum is an obligate intracellular protozoan parasite causing serious reproductive disorders in large and small ruminants worldwide. Polymorphonuclear neutrophils (PMN) react against multiple invading pathogens through different mechanisms including the release of neutrophil extracellular...

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Veröffentlicht in:	Developmental and comparative immunology 2017-07, Vol.72, p.119-127
Hauptverfasser:	Villagra-Blanco, R., Silva, L.M.R., Gärtner, U., Wagner, H., Failing, K., Wehrend, A., Taubert, A., Hermosilla, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Animals Autophagy C-Reactive Protein - metabolism Caprine Cathepsin B Cathepsin B - metabolism Cells, Cultured Coccidiosis - immunology Deoxyribonucleic acid DNA Elastase Extracellular Traps - metabolism Extrusion Filaments Goats - immunology Histones Histones - metabolism Host-Parasite Interactions Immune response Immune system Immunity, Innate Immunofluorescence Immunology Infertility - immunology Inhibition Leukocyte Elastase - metabolism Leukocytes (neutrophilic) Leukocytes (polymorphonuclear) Localization MAP kinase NAD(P)H oxidase Neospora - immunology Neospora caninum Neosporosis Neutrophil extracellular traps Neutrophils Neutrophils - immunology Neutrophils - parasitology NOX Parasites Pentraxins Phagocytosis PI3K Protozoa Reproductive disorders Scanning electron microscopy Signal Transduction Signaling SOCE Tachyzoites
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