PHA665752 inhibits the HGF-stimulated migration and invasion of cells by blocking PI3K/AKT pathway in uveal melanoma

HGF/c-MET is frequently associated with tumor metastasis in many cancers, including uveal melanoma (UM). PHA665752, a selective c-MET inhibitor, exhibits anticancer activity through inhibiting cell motility in some cancers. In this study, we investigated the effects of PHA665752 on UM cell lines M17...

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Veröffentlicht in:	Neoplasma 2017, Vol.64 (3), p.377-388
Hauptverfasser:	Wang, Z, He, C, Liu, L, Ma, N, Chen, X, Zheng, D, Qiu, G H
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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