Association of a functional 17β-estradiol sensitive IL6-174G/C promoter polymorphism with early-onset type 1 diabetes in females

The type 1 diabetes mellitus (T1DM) candidate gene SNP IL6-174G/C was genotyped in 253 Danish T1DM families (1129 individuals). TDT analysis demonstrated linkage in the presence of association between the IL6-174C allele and T1DM in the 416 T1DM offspring, Ptdt=0.04. Gender conditioned TDT analyses...

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Veröffentlicht in:	Human molecular genetics 2003-05, Vol.12 (10), p.1101-1110
Hauptverfasser:	Kristiansen, Ole P., Nolsøe, Runa L., Larsen, Lykke, Gjesing, Anette M.P., Johannesen, Jesper, Larsen, Zenia M., Lykkesfeldt, Anne E., Karlsen, Allan E., Pociot, Flemming, Mandrup-Poulsen, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Fundamental and applied biological sciences. Psychology Molecular and cellular biology
Online-Zugang:	Volltext
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