Structural Basis for the Molecular Recognition between Human Splicing Factors U2AF and SF1/mBBP

The essential splicing factors SF1 and U2AF play an important role in the recognition of the pre-mRNA 3' splice site during early spliceosome assembly. The structure of the C-terminal RRM (RRM3) of human U2AF super(65) complexed to an N-terminal peptide of SF1 reveals an extended negatively cha...

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Veröffentlicht in:	Molecular cell 2003-04, Vol.11 (4), p.965-976
Hauptverfasser:	Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kraemer, A, Sattler, M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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