U-shaped relationship between serum uric acid levels and intrarenal hemodynamic parameters in healthy subjects

Hyperuricemia has been reported to affect renal hemodynamics. In a recent study, both low and high levels of serum uric acid (SUA) were found to be associated with loss of kidney function. The goal of this study was to evaluate the relationship between SUA levels and intrarenal hemodynamic parameter...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2017-06, Vol.312 (6), p.F992-F997
Hauptverfasser:	Uedono, Hideki, Tsuda, Akihiro, Ishimura, Eiji, Nakatani, Shinya, Kurajoh, Masafumi, Mori, Katsuhito, Uchida, Junji, Emoto, Masanori, Nakatani, Tatsuya, Inaba, Masaaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers - blood Female Glomerular Filtration Rate Healthy Volunteers Hemodynamics Humans Hyperuricemia Hyperuricemia - blood Hyperuricemia - physiopathology Infusions, Intravenous Inulin Inulin - administration & dosage Inulin - metabolism Kidney - blood supply Kidneys Male Middle Aged Models, Biological Multiple regression analysis p-Aminohippuric Acid - administration & dosage p-Aminohippuric Acid - metabolism Regression Analysis Renal Circulation Renal function Renal Plasma Flow Sensory neurons Uric acid Uric Acid - blood Variables
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