N‑Mannich Bases of Aromatic Heterocyclic Amides: Synthesis via Copper-Catalyzed Aerobic Cross-Dehydrogenative Coupling under Ambient Conditions

An efficient and facile method to synthesize N-Mannich bases has been developed using an inexpensive copper­(I) bromide/air catalyst system at ambient temperature. A cross-dehydrogenative coupling of N,N-dimethylarylamines occurs efficiently with aromatic heterocyclic amides (oxindoles, isatins), cy...

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Veröffentlicht in:	Organic letters 2017-03, Vol.19 (6), p.1322-1325
Hauptverfasser:	Singh, Shailendra K, Chandna, Nisha, Jain, Nidhi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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