A Kinase Anchoring Protein (AKAP) Interaction and Dimerization of the RIα and RIβ Regulatory Subunits of Protein Kinase A In vivo by the Yeast Two Hybrid System

Protein kinase A (PKA) regulatory (R) subunits dimerize through an N-terminal motif. Such dimerization is necessary for binding to PKA anchoring proteins (AKAPs) and targeting of PKA to its site of action. In the present study, we used the yeast two-hybrid system as an in vivo bio-reporter assay and...

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Veröffentlicht in:	Journal of molecular biology 2003-03, Vol.327 (3), p.609-618
Hauptverfasser:	Carlson, Cathrine R., Ruppelt, Anja, Taskén, Kjetil
Format:	Artikel
Sprache:	eng
Schlagworte:	AKAP PKA RI dimerization RI heterodimerization yeast two-hybrid system
Online-Zugang:	Volltext
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