Antioxidants and fetal protection against ethanol teratogenicity: I. Review of the experimental data and implications to humans

Ethanol is the most common human teratogen, and heavy drinking during pregnancy can result in serious adverse outcomes to the fetus. The cellular mechanisms by which ethanol induces damage in utero are not well understood, while induction of oxidative stress is believed to be one putative mechanism....

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Veröffentlicht in:	Neurotoxicology and Teratology 2003-01, Vol.25 (1), p.1-9
Hauptverfasser:	Cohen-Kerem, Raanan, Koren, Gideon
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol-Induced Disorders, Nervous System - drug therapy Alcohol-Induced Disorders, Nervous System - physiopathology Alcohol-Induced Disorders, Nervous System - prevention & control Alcoholism and acute alcohol poisoning Antioxidant Antioxidants - pharmacology Antioxidants - therapeutic use Ascorbic Acid - pharmacology Ascorbic Acid - therapeutic use Biological and medical sciences Central Nervous System - drug effects Central Nervous System - metabolism Central Nervous System - physiopathology Ethanol Ethanol - antagonists & inhibitors Ethanol - toxicity Female Fetal Alcohol Spectrum Disorders - drug therapy Fetal Alcohol Spectrum Disorders - physiopathology Fetal Alcohol Spectrum Disorders - prevention & control Fetus - drug effects Fetus - pathology Fetus - physiopathology Humans Medical sciences Oxidative Stress - drug effects Oxidative Stress - physiology Pregnancy Teratogenicity Toxicology Vitamin E - pharmacology Vitamin E - therapeutic use
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