Effects of structured patient education in adults with atopic dermatitis: Multicenter randomized controlled trial
Background Atopic dermatitis (AD) is a chronic relapsing skin disease prevalent in 1% to 3% of adults in Western industrialized countries. Objective We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of life, symptoms, and...
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| creator | Heratizadeh, Annice, MD Werfel, Thomas, MD Wollenberg, Andreas, MD Abraham, Susanne, MD Plank-Habibi, Sibylle Schnopp, Christina, MD Sticherling, Michael, MD Apfelbacher, Christian, PhD Biedermann, Tilo, MD Breuer, Kristine, MD Fell, Isabel, MD Fölster-Holst, Regina, MD Heine, Guido, MD Grimm, Jennifer Hennighausen, Lars, PhD Kugler, Claudia Reese, Imke, PhD Ring, Johannes, MD Schäkel, Knut, MD Schmitt, Jochen, MD, MPH Seikowski, Kurt, PhD von Stebut, Esther, MD Wagner, Nicola, MD Waßmann-Otto, Anja, PhD Wienke-Graul, Ute, MD Weisshaar, Elke, MD Worm, Margitta, MD Gieler, Uwe, MD Kupfer, Joerg, PhD |
| description | Background Atopic dermatitis (AD) is a chronic relapsing skin disease prevalent in 1% to 3% of adults in Western industrialized countries. Objective We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of life, symptoms, and severity in adults with AD. Methods In this German prospective, randomized controlled multicenter study, adult patients with moderate-to-severe AD were educated by referring to a comprehensive 12-hour training manual consented by a multiprofessional study group from different centers (Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene [ARNE]). Patients were randomly allocated to the intervention or waiting control groups. Study visits were performed at baseline and after 1 year (1 year of follow-up). Primary outcomes were defined as a decrease in (1) “catastrophizing cognitions” with respect to itching (Juckreiz-Kognitions-Fragebogen questionnaire), (2) “social anxiety” (Marburger Hautfragebogen questionnaire), (3) subjective burden by symptoms of the disease (Skindex-29 questionnaire), and (4) improvement of disease signs and symptoms assessed by using the SCORAD index at 1 year of follow-up. Data were analyzed on an intention-to-treat basis. Results At 1 year of follow-up, patients from the intervention group (n = 168) showed a significantly better improvement compared with the waiting group (n = 147) in the following defined primary study outcomes: coping behavior with respect to itching ( P |
| doi_str_mv | 10.1016/j.jaci.2017.01.029 |
| format | Article |
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Objective We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of life, symptoms, and severity in adults with AD. Methods In this German prospective, randomized controlled multicenter study, adult patients with moderate-to-severe AD were educated by referring to a comprehensive 12-hour training manual consented by a multiprofessional study group from different centers (Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene [ARNE]). Patients were randomly allocated to the intervention or waiting control groups. Study visits were performed at baseline and after 1 year (1 year of follow-up). Primary outcomes were defined as a decrease in (1) “catastrophizing cognitions” with respect to itching (Juckreiz-Kognitions-Fragebogen questionnaire), (2) “social anxiety” (Marburger Hautfragebogen questionnaire), (3) subjective burden by symptoms of the disease (Skindex-29 questionnaire), and (4) improvement of disease signs and symptoms assessed by using the SCORAD index at 1 year of follow-up. Data were analyzed on an intention-to-treat basis. Results At 1 year of follow-up, patients from the intervention group (n = 168) showed a significantly better improvement compared with the waiting group (n = 147) in the following defined primary study outcomes: coping behavior with respect to itching ( P < .001), quality of life assessed by using the Skindex-29 questionnaire ( P < .001), and the SCORAD index ( P < .001). Conclusions This is the first randomized, controlled multicenter study on patient education in adult AD. The ARNE training program shows significant beneficial effects on a variety of psychosocial parameters, as well as AD severity.</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/j.jaci.2017.01.029</identifier><identifier>PMID: 28242304</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adaptation, Psychological ; Adult ; adulthood ; Adults ; Allergy and Immunology ; Anxiety ; Atopic dermatitis ; Chronic illnesses ; Coping ; Coping behavior ; Data processing ; Dermatitis ; Dermatitis, Atopic - psychology ; Dermatitis, Atopic - therapy ; Dermatology ; disease severity ; Eczema ; Female ; Health care ; Humans ; Itching ; Male ; Middle Aged ; Motivation ; multi-professional ; Neurodegenerative diseases ; Patient education ; Patient Education as Topic ; Patient satisfaction ; Pruritus ; psychosocial ; Quality of Life ; Randomization ; Severity of Illness Index ; Skin diseases ; Training ; Young Adult</subject><ispartof>Journal of allergy and clinical immunology, 2017-09, Vol.140 (3), p.845-853.e3</ispartof><rights>American Academy of Allergy, Asthma & Immunology</rights><rights>2017 American Academy of Allergy, Asthma & Immunology</rights><rights>Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Science Ltd. Sep 1, 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c439t-eb6fce0c25fd43b33204c5da06475603dc1a5d99fb3d3e5ff2c8f51a93ecabc13</citedby><cites>FETCH-LOGICAL-c439t-eb6fce0c25fd43b33204c5da06475603dc1a5d99fb3d3e5ff2c8f51a93ecabc13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0091674917303238$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28242304$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Heratizadeh, Annice, MD</creatorcontrib><creatorcontrib>Werfel, Thomas, MD</creatorcontrib><creatorcontrib>Wollenberg, Andreas, MD</creatorcontrib><creatorcontrib>Abraham, Susanne, MD</creatorcontrib><creatorcontrib>Plank-Habibi, Sibylle</creatorcontrib><creatorcontrib>Schnopp, Christina, MD</creatorcontrib><creatorcontrib>Sticherling, Michael, MD</creatorcontrib><creatorcontrib>Apfelbacher, Christian, PhD</creatorcontrib><creatorcontrib>Biedermann, Tilo, MD</creatorcontrib><creatorcontrib>Breuer, Kristine, MD</creatorcontrib><creatorcontrib>Fell, Isabel, MD</creatorcontrib><creatorcontrib>Fölster-Holst, Regina, MD</creatorcontrib><creatorcontrib>Heine, Guido, MD</creatorcontrib><creatorcontrib>Grimm, Jennifer</creatorcontrib><creatorcontrib>Hennighausen, Lars, PhD</creatorcontrib><creatorcontrib>Kugler, Claudia</creatorcontrib><creatorcontrib>Reese, Imke, PhD</creatorcontrib><creatorcontrib>Ring, Johannes, MD</creatorcontrib><creatorcontrib>Schäkel, Knut, MD</creatorcontrib><creatorcontrib>Schmitt, Jochen, MD, MPH</creatorcontrib><creatorcontrib>Seikowski, Kurt, PhD</creatorcontrib><creatorcontrib>von Stebut, Esther, MD</creatorcontrib><creatorcontrib>Wagner, Nicola, MD</creatorcontrib><creatorcontrib>Waßmann-Otto, Anja, PhD</creatorcontrib><creatorcontrib>Wienke-Graul, Ute, MD</creatorcontrib><creatorcontrib>Weisshaar, Elke, MD</creatorcontrib><creatorcontrib>Worm, Margitta, MD</creatorcontrib><creatorcontrib>Gieler, Uwe, MD</creatorcontrib><creatorcontrib>Kupfer, Joerg, PhD</creatorcontrib><creatorcontrib>Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene (ARNE) Study Group</creatorcontrib><title>Effects of structured patient education in adults with atopic dermatitis: Multicenter randomized controlled trial</title><title>Journal of allergy and clinical immunology</title><addtitle>J Allergy Clin Immunol</addtitle><description>Background Atopic dermatitis (AD) is a chronic relapsing skin disease prevalent in 1% to 3% of adults in Western industrialized countries. Objective We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of life, symptoms, and severity in adults with AD. Methods In this German prospective, randomized controlled multicenter study, adult patients with moderate-to-severe AD were educated by referring to a comprehensive 12-hour training manual consented by a multiprofessional study group from different centers (Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene [ARNE]). Patients were randomly allocated to the intervention or waiting control groups. Study visits were performed at baseline and after 1 year (1 year of follow-up). Primary outcomes were defined as a decrease in (1) “catastrophizing cognitions” with respect to itching (Juckreiz-Kognitions-Fragebogen questionnaire), (2) “social anxiety” (Marburger Hautfragebogen questionnaire), (3) subjective burden by symptoms of the disease (Skindex-29 questionnaire), and (4) improvement of disease signs and symptoms assessed by using the SCORAD index at 1 year of follow-up. Data were analyzed on an intention-to-treat basis. Results At 1 year of follow-up, patients from the intervention group (n = 168) showed a significantly better improvement compared with the waiting group (n = 147) in the following defined primary study outcomes: coping behavior with respect to itching ( P < .001), quality of life assessed by using the Skindex-29 questionnaire ( P < .001), and the SCORAD index ( P < .001). Conclusions This is the first randomized, controlled multicenter study on patient education in adult AD. The ARNE training program shows significant beneficial effects on a variety of psychosocial parameters, as well as AD severity.</description><subject>Adaptation, Psychological</subject><subject>Adult</subject><subject>adulthood</subject><subject>Adults</subject><subject>Allergy and Immunology</subject><subject>Anxiety</subject><subject>Atopic dermatitis</subject><subject>Chronic illnesses</subject><subject>Coping</subject><subject>Coping behavior</subject><subject>Data processing</subject><subject>Dermatitis</subject><subject>Dermatitis, Atopic - psychology</subject><subject>Dermatitis, Atopic - therapy</subject><subject>Dermatology</subject><subject>disease severity</subject><subject>Eczema</subject><subject>Female</subject><subject>Health care</subject><subject>Humans</subject><subject>Itching</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Motivation</subject><subject>multi-professional</subject><subject>Neurodegenerative diseases</subject><subject>Patient education</subject><subject>Patient Education as Topic</subject><subject>Patient satisfaction</subject><subject>Pruritus</subject><subject>psychosocial</subject><subject>Quality of Life</subject><subject>Randomization</subject><subject>Severity of Illness Index</subject><subject>Skin diseases</subject><subject>Training</subject><subject>Young 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MD</creator><creator>Plank-Habibi, Sibylle</creator><creator>Schnopp, Christina, MD</creator><creator>Sticherling, Michael, MD</creator><creator>Apfelbacher, Christian, PhD</creator><creator>Biedermann, Tilo, MD</creator><creator>Breuer, Kristine, MD</creator><creator>Fell, Isabel, MD</creator><creator>Fölster-Holst, Regina, MD</creator><creator>Heine, Guido, MD</creator><creator>Grimm, Jennifer</creator><creator>Hennighausen, Lars, PhD</creator><creator>Kugler, Claudia</creator><creator>Reese, Imke, PhD</creator><creator>Ring, Johannes, MD</creator><creator>Schäkel, Knut, MD</creator><creator>Schmitt, Jochen, MD, MPH</creator><creator>Seikowski, Kurt, PhD</creator><creator>von Stebut, Esther, MD</creator><creator>Wagner, Nicola, MD</creator><creator>Waßmann-Otto, Anja, PhD</creator><creator>Wienke-Graul, Ute, MD</creator><creator>Weisshaar, Elke, MD</creator><creator>Worm, Margitta, MD</creator><creator>Gieler, Uwe, MD</creator><creator>Kupfer, Joerg, PhD</creator><general>Elsevier 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Esther, MD ; Wagner, Nicola, MD ; Waßmann-Otto, Anja, PhD ; Wienke-Graul, Ute, MD ; Weisshaar, Elke, MD ; Worm, Margitta, MD ; Gieler, Uwe, MD ; Kupfer, Joerg, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-eb6fce0c25fd43b33204c5da06475603dc1a5d99fb3d3e5ff2c8f51a93ecabc13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adaptation, Psychological</topic><topic>Adult</topic><topic>adulthood</topic><topic>Adults</topic><topic>Allergy and Immunology</topic><topic>Anxiety</topic><topic>Atopic dermatitis</topic><topic>Chronic illnesses</topic><topic>Coping</topic><topic>Coping behavior</topic><topic>Data processing</topic><topic>Dermatitis</topic><topic>Dermatitis, Atopic - psychology</topic><topic>Dermatitis, Atopic - therapy</topic><topic>Dermatology</topic><topic>disease severity</topic><topic>Eczema</topic><topic>Female</topic><topic>Health 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Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Heratizadeh, Annice, MD</au><au>Werfel, Thomas, MD</au><au>Wollenberg, Andreas, MD</au><au>Abraham, Susanne, MD</au><au>Plank-Habibi, Sibylle</au><au>Schnopp, Christina, MD</au><au>Sticherling, Michael, MD</au><au>Apfelbacher, Christian, PhD</au><au>Biedermann, Tilo, MD</au><au>Breuer, Kristine, MD</au><au>Fell, Isabel, MD</au><au>Fölster-Holst, Regina, MD</au><au>Heine, Guido, MD</au><au>Grimm, Jennifer</au><au>Hennighausen, Lars, PhD</au><au>Kugler, Claudia</au><au>Reese, Imke, PhD</au><au>Ring, Johannes, MD</au><au>Schäkel, Knut, MD</au><au>Schmitt, Jochen, MD, MPH</au><au>Seikowski, Kurt, PhD</au><au>von Stebut, Esther, MD</au><au>Wagner, Nicola, MD</au><au>Waßmann-Otto, Anja, PhD</au><au>Wienke-Graul, Ute, MD</au><au>Weisshaar, Elke, MD</au><au>Worm, Margitta, MD</au><au>Gieler, Uwe, MD</au><au>Kupfer, Joerg, PhD</au><aucorp>Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene (ARNE) Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of structured patient education in adults with atopic dermatitis: Multicenter randomized controlled trial</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><addtitle>J Allergy Clin Immunol</addtitle><date>2017-09-01</date><risdate>2017</risdate><volume>140</volume><issue>3</issue><spage>845</spage><epage>853.e3</epage><pages>845-853.e3</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><abstract>Background Atopic dermatitis (AD) is a chronic relapsing skin disease prevalent in 1% to 3% of adults in Western industrialized countries. Objective We sought to investigate the effectiveness of educational training in an outpatient setting on coping with the disease, quality of life, symptoms, and severity in adults with AD. Methods In this German prospective, randomized controlled multicenter study, adult patients with moderate-to-severe AD were educated by referring to a comprehensive 12-hour training manual consented by a multiprofessional study group from different centers (Arbeitsgemeinschaft Neurodermitisschulung für Erwachsene [ARNE]). Patients were randomly allocated to the intervention or waiting control groups. Study visits were performed at baseline and after 1 year (1 year of follow-up). Primary outcomes were defined as a decrease in (1) “catastrophizing cognitions” with respect to itching (Juckreiz-Kognitions-Fragebogen questionnaire), (2) “social anxiety” (Marburger Hautfragebogen questionnaire), (3) subjective burden by symptoms of the disease (Skindex-29 questionnaire), and (4) improvement of disease signs and symptoms assessed by using the SCORAD index at 1 year of follow-up. Data were analyzed on an intention-to-treat basis. Results At 1 year of follow-up, patients from the intervention group (n = 168) showed a significantly better improvement compared with the waiting group (n = 147) in the following defined primary study outcomes: coping behavior with respect to itching ( P < .001), quality of life assessed by using the Skindex-29 questionnaire ( P < .001), and the SCORAD index ( P < .001). Conclusions This is the first randomized, controlled multicenter study on patient education in adult AD. The ARNE training program shows significant beneficial effects on a variety of psychosocial parameters, as well as AD severity.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>28242304</pmid><doi>10.1016/j.jaci.2017.01.029</doi></addata></record> |
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| language | eng |
| recordid | cdi_proquest_miscellaneous_1872884818 |
| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adaptation, Psychological Adult adulthood Adults Allergy and Immunology Anxiety Atopic dermatitis Chronic illnesses Coping Coping behavior Data processing Dermatitis Dermatitis, Atopic - psychology Dermatitis, Atopic - therapy Dermatology disease severity Eczema Female Health care Humans Itching Male Middle Aged Motivation multi-professional Neurodegenerative diseases Patient education Patient Education as Topic Patient satisfaction Pruritus psychosocial Quality of Life Randomization Severity of Illness Index Skin diseases Training Young Adult |
| title | Effects of structured patient education in adults with atopic dermatitis: Multicenter randomized controlled trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T03%3A14%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20structured%20patient%20education%20in%20adults%20with%20atopic%20dermatitis:%20Multicenter%20randomized%20controlled%20trial&rft.jtitle=Journal%20of%20allergy%20and%20clinical%20immunology&rft.au=Heratizadeh,%20Annice,%20MD&rft.aucorp=Arbeitsgemeinschaft%20Neurodermitisschulung%20f%C3%BCr%20Erwachsene%20(ARNE)%20Study%20Group&rft.date=2017-09-01&rft.volume=140&rft.issue=3&rft.spage=845&rft.epage=853.e3&rft.pages=845-853.e3&rft.issn=0091-6749&rft.eissn=1097-6825&rft_id=info:doi/10.1016/j.jaci.2017.01.029&rft_dat=%3Cproquest_cross%3E1872884818%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1937794766&rft_id=info:pmid/28242304&rft_els_id=1_s2_0_S0091674917303238&rfr_iscdi=true |