Discrete Element Framework for Modelling Extracellular Matrix, Deformable Cells and Subcellular Components: e1004544

This paper presents a framework for modelling biological tissues based on discrete particles. Cell components (e.g. cell membranes, cell cytoskeleton, cell nucleus) and extracellular matrix (e.g. collagen) are represented using collections of particles. Simple particle to particle interaction laws a...

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Veröffentlicht in:	PLoS computational biology 2015-10, Vol.11 (10)
Hauptverfasser:	Gardiner, Bruce S, Wong, Kelvin KL, Joldes, Grand R, Rich, Addison J, Tan, Chin Wee, Burgess, Antony W, Smith, David W
Format:	Artikel
Sprache:	eng
Schlagworte:	Atoms & subatomic particles Behavior Cell adhesion & migration Cell growth Experiments Extracellular matrix Flexibility Mechanics Methods Morphology Partial differential equations Signal transduction
Online-Zugang:	Volltext
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