Anticancer effects of cantharidin in A431 human skin cancer (Epidermoid carcinoma) cells in vitro and in vivo

ABSTRACT Cantharidin (CTD), a potential anticancer agent of Traditional Chinese Medicine has cytotxic effects in different human cancer cell lines. The cytotoxic effects of CTD on A431 human skin cancer (epidermoid carcinoma) cells in vitro and in A431 cell xenograft mouse model were examined. In vi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Environmental toxicology 2017-03, Vol.32 (3), p.723-738
Hauptverfasser:	Li, Chi‐Chuan, Yu, Fu‐Shun, Fan, Ming‐Jen, Chen, Ya‐Yin, Lien, Jin‐Cherng, Chou, Yu‐Cheng, Lu, Hsu‐Feng, Tang, Nou‐Ying, Peng, Shu‐Fen, Huang, Wen‐Wen, Chung, Jing‐Gung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - therapeutic use Antineoplastic Agents - toxicity apoptosis Apoptosis - drug effects cantharidin Cantharidin - therapeutic use Cantharidin - toxicity Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Caspases - genetics Caspases - metabolism cell cycle Cell Line, Tumor Cell Survival - drug effects Cyclin D - metabolism Cytochromes c - metabolism DNA Fragmentation - drug effects G1 Phase Cell Cycle Checkpoints - drug effects human skin cancer cells Humans Male Membrane Potential, Mitochondrial - drug effects Mice Mice, Inbred BALB C Mice, Nude Reactive Oxygen Species - metabolism Receptors, Death Domain - metabolism Signal Transduction - drug effects Skin Neoplasms - drug therapy Skin Neoplasms - metabolism Skin Neoplasms - pathology TNF-Related Apoptosis-Inducing Ligand - metabolism Transplantation, Heterologous
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!