Effects on the reproductive parameters of two generations of Rattus norvegicus offspring from dams exposed to heptachlor during gestation and lactation

ABSTRACT Heptachlor has been targeted for global elimination because of its toxicity and environmental persistence, in accordance with the Stockholm Convention on Persistent Organic Pollutants (POPs). However, there is no regulation of heptachlor use in Mexico, where relatively high levels have been...

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Veröffentlicht in:	Environmental toxicology 2017-03, Vol.32 (3), p.856-868
Hauptverfasser:	Martínez‐Ibarra, Alejandra, Morimoto, Sumiko, Cerbón, Marco, Prado‐Flores, Guadalupe
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cervix Uteri - metabolism Cervix Uteri - pathology endocrine disruptor Endocrine Disruptors - toxicity Estrogen Receptor alpha - metabolism Female heptachlor Heptachlor - toxicity Immunohistochemistry Insecticides - toxicity Lactation Male Milk - chemistry organochlorines Pregnancy Prenatal Exposure Delayed Effects Progesterone - blood Puberty - drug effects Rats Rats, Wistar Rattus norvegicus Receptors, Progesterone - metabolism Reproduction - drug effects reproductive toxicology steroid hormone receptors Up-Regulation - drug effects
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