The role of oncolytic virus immunotherapies to subvert cancer immune evasion

Despite huge economic and intellectual investments, developing effective cancer treatments continues to be an overarching challenge. Engineered oncolytic viruses (OVs) present self-amplifying immunotherapy platforms capable of preferential cytotoxicity to cancer cells and simultaneous activation of...

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Veröffentlicht in:	Future oncology (London, England) England), 2015-02, Vol.11 (4), p.675-689
Hauptverfasser:	Workenhe, Samuel T, Verschoor, Meghan L, Mossman, Karen L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical engineering cancer immunotherapy Cancer research Cancer treatment Combined Modality Therapy Health aspects Humans Immune Tolerance - immunology Immunologic Surveillance Immunotherapy - methods Neoplasms - genetics Neoplasms - immunology Neoplasms - metabolism Neoplasms - therapy Oncolytic Virotherapy - methods oncolytic virus Oncolytic Viruses - genetics Oncolytic Viruses - immunology Tumor Escape - genetics Tumor Escape - immunology Virus Replication - immunology
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