Chemotherapy alters cisatracurium induced neuromuscular blockade characteristics: A prospective cohort study

Abstract Study objective To compare the characteristics of NMDR induced muscle paralysis in breast cancer patients with and without a history of recent chemotherapy with cyclophosphamide, doxorubicin and 5-fluorouracil (CAF) regimen. Design This is a non-randomized prospective cohort study. Setting...

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Veröffentlicht in:	Journal of clinical anesthesia 2017-02, Vol.36, p.84-87
Hauptverfasser:	Zanjani, Amir Poya, MD, Maghsoudloo, Maziar, MD, Makarem, Jalil, MD, Farokhnia, Fahimeh, MD, Fazli, Morteza, Khan, Zahid Hussain, MD, FCCM
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia & Perioperative Care Anesthesia, General - methods Antineoplastic Combined Chemotherapy Protocols - pharmacology Atracurium - administration & dosage Atracurium - analogs & derivatives Atracurium - antagonists & inhibitors Atracurium - pharmacology Body temperature Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - surgery Cancer therapies Chemotherapy Chemotherapy, Adjuvant Cisatracurium Cohort analysis Cyclophosphamide - pharmacology Doxorubicin Doxorubicin - pharmacology Drug Administration Schedule Drug dosages Electrolytes Female Fluorouracil - pharmacology General anesthesia Humans Hypotheses Intubation Mastectomy Metabolism Middle Aged Monitoring, Intraoperative - methods Neoadjuvant Therapy - methods Neuromuscular Blockade - methods Neuromuscular blocking agents Neuromuscular Junction - drug effects Neuromuscular Nondepolarizing Agents - administration & dosage Neuromuscular Nondepolarizing Agents - antagonists & inhibitors Neuromuscular Nondepolarizing Agents - pharmacology Pain Medicine Prospective Studies
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