The Biodistribution and Immune Suppressive Effects of Breast Cancer-Derived Exosomes

Small membranous secretions from tumor cells, termed exosomes, contribute significantly to intercellular communication and subsequent reprogramming of the tumor microenvironment. Here, we use optical imaging to determine that exogenously administered fluorescently labeled exosomes derived from highl...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2016-12, Vol.76 (23), p.6816-6827
Hauptverfasser:	Wen, Shu Wen, Sceneay, Jaclyn, Lima, Luize Goncalves, Wong, Christina S F, Becker, Melanie, Krumeich, Sophie, Lobb, Richard J, Castillo, Vanessa, Wong, Ke Ni, Ellis, Sarah, Parker, Belinda S, Möller, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - immunology Breast Neoplasms - pathology Cell Proliferation Exosomes - metabolism Female Humans Immunosuppression - methods Mice Mice, Inbred BALB C Mice, Inbred C57BL
Online-Zugang:	Volltext
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