Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury

Proton pump inhibitor (PPI) use is associated with an increased risk of acute kidney injury (AKI), incident chronic kidney disease (CKD), and progression to end-stage renal disease (ESRD). PPI-associated CKD is presumed to be mediated by intervening AKI. However, whether PPI use is associated with a...

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Veröffentlicht in:	Kidney international 2017-06, Vol.91 (6), p.1482-1494
Hauptverfasser:	Xie, Yan, Bowe, Benjamin, Li, Tingting, Xian, Hong, Yan, Yan, Al-Aly, Ziyad
Format:	Artikel
Sprache:	eng
Schlagworte:	acute kidney injury Acute Kidney Injury - chemically induced Acute Kidney Injury - diagnosis Acute Kidney Injury - epidemiology Adult Aged chronic kidney disease clinical nephrology Comorbidity Databases, Factual Disease Progression Drug Administration Schedule Female Glomerular Filtration Rate - drug effects Histamine H2 Antagonists - administration & dosage Histamine H2 Antagonists - adverse effects Humans Incidence Kidney - drug effects Kidney - pathology Kidney - physiopathology Kidney Failure, Chronic - chemically induced Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - epidemiology Male Middle Aged Prognosis Proton Pump Inhibitors - administration & dosage Proton Pump Inhibitors - adverse effects Risk Factors Time Factors United States - epidemiology United States Department of Veterans Affairs
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