MicroRNAs in Lung Development and Disease

Summary MicroRNAs (miRNAs) are small (∼22 nucleotides), non-coding RNA molecules that regulate gene expression post-transcriptionally by inhibiting target mRNAs. Research into the roles of miRNAs in lung development and disease is at the early stages. In this review, we discuss the role of miRNAs in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Paediatric respiratory reviews 2017-03, Vol.22, p.38-43
Hauptverfasser:	Ameis, Dustin, Khoshgoo, Naghmeh, Iwasiow, Barbara M, Snarr, Phillip, Keijzer, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals asthma Asthma - genetics bronchopulmonary dysplasia Bronchopulmonary Dysplasia - genetics cystic fibrosis Cystic Fibrosis - genetics Gene Expression Gene Expression Regulation, Developmental Humans Lung - embryology Lung - growth & development lung development Lung Diseases - genetics MicroRNAs MicroRNAs - genetics Pediatrics Pulmonary/Respiratory
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Summary MicroRNAs (miRNAs) are small (∼22 nucleotides), non-coding RNA molecules that regulate gene expression post-transcriptionally by inhibiting target mRNAs. Research into the roles of miRNAs in lung development and disease is at the early stages. In this review, we discuss the role of miRNAs in pediatric respiratory disease, including cystic fibrosis, asthma, and bronchopulmonary dysplasia.
ISSN:	1526-0542 1526-0550
DOI:	10.1016/j.prrv.2016.12.002