Evaluation and identification of factors related to KRAS and BRAF gene mutations in colorectal cancer: A meta-analysis

The aim of this meta-analysis is to evaluate the distribution pattern of KRAS and BRAF mutations in colorectal cancer. The database was searched without language restrictions. Meta-analyses were conducted using the STATA software. We calculated the odds ratio (OR) and its 95% confidence interval (95...

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Veröffentlicht in:	Journal of cancer research and therapeutics 2016-12, Vol.12 (Supplement), p.C191-C198
Hauptverfasser:	Lin, Li, Chen, Guang-Yong, Xu, Chun-Wei, Wang, Hai-Yan, Wu, Yong-Fang, Fang, Mei-Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Care and treatment Clinical trials Colorectal cancer Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics CpG Islands Development and progression DNA Methylation Evaluation Gene Expression Regulation, Neoplastic Gene mutation Genetic aspects Genetic Association Studies Genetic Predisposition to Disease Health aspects Humans Microsatellite Instability Molecular diagnostic techniques Mutation Odds Ratio Phenotype Proto-Oncogene Proteins B-raf - genetics Publication Bias ras Proteins - genetics
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