Antibacterial efficacy of several intracanal medicaments for endodontic therapy
The antibacterial efficacy of intracanal medicaments for 2 and 7 days, in open apex root canals contaminated with Enterococcus faecalis biofilms was compared. One hundred and thirty-eight standardized uniradicular human roots were inoculated with E. faecalis. Colony forming units (CFU) were recorded...
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Veröffentlicht in: | Dental Materials Journal 2017/05/30, Vol.36(3), pp.319-324 |
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description | The antibacterial efficacy of intracanal medicaments for 2 and 7 days, in open apex root canals contaminated with Enterococcus faecalis biofilms was compared. One hundred and thirty-eight standardized uniradicular human roots were inoculated with E. faecalis. Colony forming units (CFU) were recorded before and after medication. Samples were divided in two (2/7 days), and subdivided (n=8/group): triple antibiotic paste (TAP); double antibiotic paste (DAP); dental base paste (DBP), consisting of calcium hydroxide, propylene glycol and calcium carbonate; DBP+0.2% chlorhexidine (CHX); DBP+0.2% cetrimide (CTR); DBP+0.2% CHX+0.2% CTR; 2.5% sodium hypochlorite (NaOCl); and distilled water. At both periods TAP, DAP, DBP+0.2% CHX, DBP+0.2% CTR and DBP+0.2% CHX+0.2% CTR exhibited no growth (NG) of E. faecalis. Distilled water and 2.5% NaOCl obtained the lowest CFU reduction. No growth with DBP was reached only at 7 days. CHX and/or CTR pastes were as effective as DAP and TAP. A 2-day period provided an effective disinfection. |
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Victoria ; RUIZ-LINARES, Matilde ; FERRER-LUQUE, Carmen María</creator><creatorcontrib>VALVERDE, Marta E. ; BACA, Pilar ; CEBALLOS, Laura ; FUENTES, M. Victoria ; RUIZ-LINARES, Matilde ; FERRER-LUQUE, Carmen María ; Health Sciences Faculty ; Department of Stomatology ; Campus de Cartuja ; School of Dentistry ; Rey Juan Carlos University ; Stomatology Area ; University of Granada</creatorcontrib><description>The antibacterial efficacy of intracanal medicaments for 2 and 7 days, in open apex root canals contaminated with Enterococcus faecalis biofilms was compared. One hundred and thirty-eight standardized uniradicular human roots were inoculated with E. faecalis. Colony forming units (CFU) were recorded before and after medication. Samples were divided in two (2/7 days), and subdivided (n=8/group): triple antibiotic paste (TAP); double antibiotic paste (DAP); dental base paste (DBP), consisting of calcium hydroxide, propylene glycol and calcium carbonate; DBP+0.2% chlorhexidine (CHX); DBP+0.2% cetrimide (CTR); DBP+0.2% CHX+0.2% CTR; 2.5% sodium hypochlorite (NaOCl); and distilled water. At both periods TAP, DAP, DBP+0.2% CHX, DBP+0.2% CTR and DBP+0.2% CHX+0.2% CTR exhibited no growth (NG) of E. faecalis. Distilled water and 2.5% NaOCl obtained the lowest CFU reduction. No growth with DBP was reached only at 7 days. CHX and/or CTR pastes were as effective as DAP and TAP. A 2-day period provided an effective disinfection.</description><identifier>ISSN: 0287-4547</identifier><identifier>EISSN: 1881-1361</identifier><identifier>DOI: 10.4012/dmj.2016-102</identifier><identifier>PMID: 28228624</identifier><language>eng</language><publisher>Japan: The Japanese Society for Dental Materials and Devices</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Antiinfectives and antibacterials ; Bacterial proteins ; Biofilms ; Calcium ; Calcium carbonate ; Calcium hydroxide ; Cetrimide ; Chlorhexidine ; Chlorhexidine - therapeutic use ; Dental Pulp Cavity ; Dental roots ; Dentistry ; Disinfection ; Distilled water ; Double antibiotic paste ; Enterococcus faecalis ; Humans ; Pastes ; Propylene ; Propylene glycol ; Regenerative endodontic therapy ; Root Canal Irrigants - therapeutic use ; Root canals ; Slaked lime ; Sodium ; Sodium hypochlorite ; Sodium Hypochlorite - therapeutic use</subject><ispartof>Dental Materials Journal, 2017/05/30, Vol.36(3), pp.319-324</ispartof><rights>2017 The Japanese Society for Dental Materials and Devices</rights><rights>Copyright Japan Science and Technology Agency 2017</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c671t-f7540ba174a84ff0050855e14c8f360f2ee44ba5b992dbc00996827c2d7680e13</citedby><cites>FETCH-LOGICAL-c671t-f7540ba174a84ff0050855e14c8f360f2ee44ba5b992dbc00996827c2d7680e13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28228624$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VALVERDE, Marta E.</creatorcontrib><creatorcontrib>BACA, Pilar</creatorcontrib><creatorcontrib>CEBALLOS, Laura</creatorcontrib><creatorcontrib>FUENTES, M. Victoria</creatorcontrib><creatorcontrib>RUIZ-LINARES, Matilde</creatorcontrib><creatorcontrib>FERRER-LUQUE, Carmen María</creatorcontrib><creatorcontrib>Health Sciences Faculty</creatorcontrib><creatorcontrib>Department of Stomatology</creatorcontrib><creatorcontrib>Campus de Cartuja</creatorcontrib><creatorcontrib>School of Dentistry</creatorcontrib><creatorcontrib>Rey Juan Carlos University</creatorcontrib><creatorcontrib>Stomatology Area</creatorcontrib><creatorcontrib>University of Granada</creatorcontrib><title>Antibacterial efficacy of several intracanal medicaments for endodontic therapy</title><title>Dental Materials Journal</title><addtitle>Dent. Mater. J.</addtitle><description>The antibacterial efficacy of intracanal medicaments for 2 and 7 days, in open apex root canals contaminated with Enterococcus faecalis biofilms was compared. One hundred and thirty-eight standardized uniradicular human roots were inoculated with E. faecalis. Colony forming units (CFU) were recorded before and after medication. Samples were divided in two (2/7 days), and subdivided (n=8/group): triple antibiotic paste (TAP); double antibiotic paste (DAP); dental base paste (DBP), consisting of calcium hydroxide, propylene glycol and calcium carbonate; DBP+0.2% chlorhexidine (CHX); DBP+0.2% cetrimide (CTR); DBP+0.2% CHX+0.2% CTR; 2.5% sodium hypochlorite (NaOCl); and distilled water. At both periods TAP, DAP, DBP+0.2% CHX, DBP+0.2% CTR and DBP+0.2% CHX+0.2% CTR exhibited no growth (NG) of E. faecalis. Distilled water and 2.5% NaOCl obtained the lowest CFU reduction. No growth with DBP was reached only at 7 days. CHX and/or CTR pastes were as effective as DAP and TAP. A 2-day period provided an effective disinfection.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Antiinfectives and antibacterials</subject><subject>Bacterial proteins</subject><subject>Biofilms</subject><subject>Calcium</subject><subject>Calcium carbonate</subject><subject>Calcium hydroxide</subject><subject>Cetrimide</subject><subject>Chlorhexidine</subject><subject>Chlorhexidine - therapeutic use</subject><subject>Dental Pulp Cavity</subject><subject>Dental roots</subject><subject>Dentistry</subject><subject>Disinfection</subject><subject>Distilled water</subject><subject>Double antibiotic paste</subject><subject>Enterococcus faecalis</subject><subject>Humans</subject><subject>Pastes</subject><subject>Propylene</subject><subject>Propylene glycol</subject><subject>Regenerative endodontic therapy</subject><subject>Root Canal Irrigants - therapeutic use</subject><subject>Root canals</subject><subject>Slaked lime</subject><subject>Sodium</subject><subject>Sodium hypochlorite</subject><subject>Sodium Hypochlorite - therapeutic use</subject><issn>0287-4547</issn><issn>1881-1361</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEFv1DAQhS0EokvhxhlF4sKhKTO2YzvHUtGCVKkXOFuOM6ZZJc5iZyvtv8dL2kXiMmPNfH4z8xh7j3ApAfnnftpeckBVI_AXbIPGYI1C4Uu2AW50LRupz9ibnLcAslXGvGZn3HBuFJcbdn8Vl6FzfqE0uLGiEAbv_KGaQ5XpkVKpDXFJzrtYnhP1pT1RXHIV5lRR7Od-Lgq-Wh4KvDu8Za-CGzO9e8rn7OfN1x_X3-q7-9vv11d3tVcalzroRkLnUEtnZAgADZimIZTeBKEgcCIpO9d0bcv7zgO0ZXOuPe-1MkAoztmnVXeX5t97youdhuxpHF2keZ8tGo1NIySogn78D93O-1TOybb4JqUy2MpCXayUT3POiYLdpWFy6WAR7NFoW4w-flClwAv-4Ul03xVXTvCzswW4XYHVs3GO4xDp3-j-AD3FVVJbgHK1sIBoQWBbApfctFq2UJS-rErbvLhfdBrlUvF9pL97CWXFMTzvd2r6B5csRfEH6Vel0w</recordid><startdate>2017</startdate><enddate>2017</enddate><creator>VALVERDE, Marta E.</creator><creator>BACA, Pilar</creator><creator>CEBALLOS, Laura</creator><creator>FUENTES, M. Victoria</creator><creator>RUIZ-LINARES, Matilde</creator><creator>FERRER-LUQUE, Carmen María</creator><general>The Japanese Society for Dental Materials and Devices</general><general>Japanese Society for Dental Materials and Devices</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QP</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>2017</creationdate><title>Antibacterial efficacy of several intracanal medicaments for endodontic therapy</title><author>VALVERDE, Marta E. ; BACA, Pilar ; CEBALLOS, Laura ; FUENTES, M. 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Victoria</au><au>RUIZ-LINARES, Matilde</au><au>FERRER-LUQUE, Carmen María</au><aucorp>Health Sciences Faculty</aucorp><aucorp>Department of Stomatology</aucorp><aucorp>Campus de Cartuja</aucorp><aucorp>School of Dentistry</aucorp><aucorp>Rey Juan Carlos University</aucorp><aucorp>Stomatology Area</aucorp><aucorp>University of Granada</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibacterial efficacy of several intracanal medicaments for endodontic therapy</atitle><jtitle>Dental Materials Journal</jtitle><addtitle>Dent. Mater. J.</addtitle><date>2017</date><risdate>2017</risdate><volume>36</volume><issue>3</issue><spage>319</spage><epage>324</epage><pages>319-324</pages><issn>0287-4547</issn><eissn>1881-1361</eissn><abstract>The antibacterial efficacy of intracanal medicaments for 2 and 7 days, in open apex root canals contaminated with Enterococcus faecalis biofilms was compared. One hundred and thirty-eight standardized uniradicular human roots were inoculated with E. faecalis. Colony forming units (CFU) were recorded before and after medication. Samples were divided in two (2/7 days), and subdivided (n=8/group): triple antibiotic paste (TAP); double antibiotic paste (DAP); dental base paste (DBP), consisting of calcium hydroxide, propylene glycol and calcium carbonate; DBP+0.2% chlorhexidine (CHX); DBP+0.2% cetrimide (CTR); DBP+0.2% CHX+0.2% CTR; 2.5% sodium hypochlorite (NaOCl); and distilled water. At both periods TAP, DAP, DBP+0.2% CHX, DBP+0.2% CTR and DBP+0.2% CHX+0.2% CTR exhibited no growth (NG) of E. faecalis. Distilled water and 2.5% NaOCl obtained the lowest CFU reduction. No growth with DBP was reached only at 7 days. CHX and/or CTR pastes were as effective as DAP and TAP. A 2-day period provided an effective disinfection.</abstract><cop>Japan</cop><pub>The Japanese Society for Dental Materials and Devices</pub><pmid>28228624</pmid><doi>10.4012/dmj.2016-102</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Anti-Bacterial Agents - therapeutic use Antibiotics Antiinfectives and antibacterials Bacterial proteins Biofilms Calcium Calcium carbonate Calcium hydroxide Cetrimide Chlorhexidine Chlorhexidine - therapeutic use Dental Pulp Cavity Dental roots Dentistry Disinfection Distilled water Double antibiotic paste Enterococcus faecalis Humans Pastes Propylene Propylene glycol Regenerative endodontic therapy Root Canal Irrigants - therapeutic use Root canals Slaked lime Sodium Sodium hypochlorite Sodium Hypochlorite - therapeutic use |
title | Antibacterial efficacy of several intracanal medicaments for endodontic therapy |
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