Secretions of Bifidobacterium infantis and Lactobacillus acidophilus Protect Intestinal Epithelial Barrier Function

ABSTRACT Objectives: The secreted metabolites of probiotics are cytoprotective to intestinal epithelium and have been shown to attenuate inflammation and reduce gut permeability. The present study was designed to determine the protective effects of probiotic conditioned media (PCM) from Bifidobacter...

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Veröffentlicht in:	Journal of pediatric gastroenterology and nutrition 2017-03, Vol.64 (3), p.404-412
Hauptverfasser:	Guo, Shuangshuang, Gillingham, Tyler, Guo, Yuming, Meng, Di, Zhu, Weishu, Walker, W. Allen, Ganguli, Kriston
Format:	Artikel
Sprache:	eng
Schlagworte:	Bifidobacterium longum subspecies infantis - metabolism Biomarkers - metabolism Blotting, Western Caco-2 Cells Caco‐2 cell monolayer Claudin-1 - metabolism Fluorescent Antibody Technique Humans IL‐1β Interleukin-1beta - metabolism Intestinal Mucosa - metabolism Lactobacillus acidophilus - metabolism NF-kappa B - metabolism NF‐κB p65 Occludin - metabolism Permeability Probiotics - metabolism tight junction Tight Junctions - metabolism
Online-Zugang:	Volltext
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