Selection of DNA aptamers for extra cellular domain of human epidermal growth factor receptor 2 to detect HER2 positive carcinomas

Background Human epidermal growth factor receptor 2 (Her2, an orphan receptor of ErbB family) is considered as an important biomarker as it plays a key role in the development and progression of aggressive types of breast, ovarian, stomach and gastric cancer. In the present study, we developed novel...

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Veröffentlicht in:	Clinical & translational oncology 2017-08, Vol.19 (8), p.976-988
Hauptverfasser:	Sett, A., Borthakur, B. B., Bora, U.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamers, Nucleotide - genetics Base Sequence Biomarkers, Tumor - genetics Breast Neoplasms - diagnosis Breast Neoplasms - genetics ErbB Receptors - genetics Female Humans Medicine Medicine & Public Health Oncology Prognosis Protein Domains Receptor, ErbB-2 - genetics Research Article SELEX Aptamer Technique Tumor Cells, Cultured
Online-Zugang:	Volltext
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