Direct Oral Anticoagulant- or Warfarin-Related Major Bleeding: Characteristics, Reversal Strategies, and Outcomes From a Multicenter Observational Study

Direct oral anticoagulants (DOACs) have expanded the armamentarium for antithrombotic therapy. Although DOAC-related major bleeding was associated with favorable outcomes compared with warfarin in clinical trials, warfarin effects were reversed in < 40% of cases, raising concerns about the genera...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chest 2017-07, Vol.152 (1), p.81-91
Hauptverfasser:	Xu, Yan, Schulman, Sam, Dowlatshahi, Dar, Holbrook, Anne M, Simpson, Christopher S, Shepherd, Lois E, Wells, Philip S, Giulivi, Antonio, Gomes, Tara, Mamdani, Muhammad, Khuu, Wayne, Frymire, Eliot, Johnson, Ana P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anticoagulants - administration & dosage Anticoagulants - adverse effects Antithrombins - administration & dosage Antithrombins - adverse effects Atrial Fibrillation - complications Blood Coagulation Factors - therapeutic use Dabigatran - administration & dosage Dabigatran - adverse effects Erythrocyte Transfusion - methods Erythrocyte Transfusion - statistics & numerical data Factor VIIa - therapeutic use Female Hemorrhage - chemically induced Hemorrhage - diagnosis Hemorrhage - mortality Hemorrhage - therapy Hospital Mortality Humans Male Medication Therapy Management - statistics & numerical data Ontario - epidemiology Recombinant Proteins - therapeutic use Retrospective Studies Stroke - etiology Stroke - prevention & control Warfarin - administration & dosage Warfarin - adverse effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!